Tan Lab | DSigDB

Gene Set: D4 : CTD - cinobufagin

Collection

D4 : CTD

Chemical Name

cinobufagin ( From PubChem : CINOBUFAGIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
442.545 g/mol	1	6	3.7999	True

Structure

InChI

InChI=1S/C26H34O6/c1-14(27)31-22-21(15-4-7-20(29)30-13-15)25(3)11-9-18-19(26(25)23(22)32-26)6-5-16-12-17(28)8-10-24(16,18)2/h4,7,13,16-19,21-23,28H,5-6,8-12H2,1-3H3

InChIKey

SCULJPGYOQQXTK-UHFFFAOYSA-N

Links

Gene (15 / 26)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	increases(expression)		BAX		C002471
CTD	decreases(expression)		BCL2		C002471
CTD	decreases(expression)		BIRC2		C002471
CTD	decreases(expression)		BIRC5		C002471
CTD	decreases(expression)		CCNA2		C002471
CTD	decreases(expression)		CDK2		C002471
CTD	decreases(expression)		CDKN1A		C002471
CTD	increases(metabolic processing)		CYP3A4		C002471
CTD	increases(reaction)		CYP3A4		C002471
CTD	increases(activity)		CYP3A4		C002471
CTD	increases(expression)		CYP3A4		C002471
CTD	decreases(reaction)		CYP3A4		C002471
CTD	increases(expression)		GSK3B		C002471
CTD	affects(response to substance)		GSK3B		C002471
CTD	decreases(expression)		GSK3B		C002471
CTD	decreases(reaction)		GSK3B		C002471
CTD	decreases(expression)		MYC		C002471
CTD	increases(expression)		PARP1		C002471
CTD	decreases(reaction)		PARP1		C002471
CTD	increases(reaction)		PARP1		C002471
CTD	decreases(expression)		PCNA		C002471
CTD	decreases(expression)		RELA		C002471
CTD	decreases(reaction)		RELA		C002471
CTD	increases(reaction)		RELA		C002471
CTD	decreases(expression)		XIAP		C002471
ChEMBL	Activity	-	CLCN3	-	Target : CHEMBL2401603

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