Tan Lab | DSigDB

Gene Set: D4 : CTD - diethyl maleate

Collection

D4 : CTD

Chemical Name

diethyl maleate ( From PubChem : 141-05-9 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
172.178 g/mol	0	4	0.6688	True

Structure

InChI

InChI=1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5+

InChIKey

IEPRKVQEAMIZSS-AATRIKPKSA-N

Links

Gene (32 / 56)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			AKR1C2		C014476
CTD	increases(expression)			APAF1		C014476
CTD	increases(expression)			ATM		C014476
CTD	increases(expression)			CASP2		C014476
CTD	increases(cleavage)			CASP3		C014476
CTD	increases(expression)			CASP3		C014476
CTD	increases(expression)			CASP9		C014476
CTD	decreases(reaction)			CBR3		C014476
CTD	increases(expression)			CBR3		C014476
CTD	decreases(expression)			CCNA1		C014476
CTD	decreases(expression)			CCND1		C014476
CTD	decreases(expression)			CCNK		C014476
CTD	decreases(reaction)			CD86		C014476
CTD	increases(expression)			CD86		C014476
CTD	increases(expression)			CDKN1A		C014476
CTD	decreases(reaction)			CXCL8		C014476
CTD	increases(expression)			CXCL8		C014476
CTD	increases(expression)			CXCL8		C014476
CTD	increases(secretion)			CXCL8		C014476
CTD	increases(stability)			CXCL8		C014476
CTD	increases(expression)			HMOX1		C014476
CTD	increases(expression)			MAFF		C014476
CTD	decreases(activity)			MGMT		C014476
CTD	increases(expression)			MT1A		C014476
CTD	increases(expression)			MT2A		C014476
CTD	affects(binding)			NFE2L2		C014476
CTD	increases(activity)			NFE2L2		C014476
CTD	increases(expression)			NQO1		C014476
CTD	affects(localization)			NUP153		C014476
CTD	affects(reaction)			NUP153		C014476
CTD	increases(O-linked glycosylation)			NUP153		C014476
CTD	increases(phosphorylation)			NUP153		C014476
CTD	affects(localization)			NUP88		C014476
CTD	affects(reaction)			NUP88		C014476
CTD	affects(cotreatment)			NUP88		C014476
CTD	increases(glycosylation)			NUP88		C014476
CTD	increases(phosphorylation)			NUP88		C014476
CTD	increases(cleavage)			PARP1		C014476
CTD	decreases(expression)			PCNA		C014476
CTD	affects(localization)			RELA		C014476
CTD	decreases(reaction)			RELA		C014476
CTD	increases(glutathionylation)			RELA		C014476
CTD	decreases(expression)			SLC40A1		C014476
CTD	decreases(reaction)			SLC40A1		C014476
CTD	increases(cleavage)			SPTAN1		C014476
CTD	affects(localization)			TNF		C014476
CTD	decreases(reaction)			TNF		C014476
CTD	increases(glutathionylation)			TNF		C014476
CTD	decreases(expression)			TRAP1		C014476
CTD	decreases(reaction)			TRAP1		C014476
CTD	decreases(response to substance)			TRAP1		C014476
CTD	decreases(activity)			TXN		C014476
CTD	increases(expression)			TXNRD1		C014476
CTD	increases(expression)			ZFP36		C014476
PubChem	Ratio Potency (uM)	uM	13.685	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	17.545	NFE2L2	-	GI(Protien) :

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