Tan Lab | DSigDB

Gene Set: D4 : CTD - Vitamin K 2

Collection

D4 : CTD

Chemical Name

Vitamin K 2 ( From PubChem : 11032-49-8 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
444.648 g/mol	0	2	8.9179	False(3/4)

Structure

InChI

InChI=1S/C31H40O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,12,14,16,18-20H,9-11,13,15,17,21H2,1-6H3/b23-14+,24-16+,25-20+

InChIKey

DKHGMERMDICWDU-GHDNBGIDSA-N

Links

Gene (14 / 28)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			BGLAP		D024482
CTD	decreases(reaction)			BGLAP		D024482
CTD	decreases(expression)			BGLAP		D024482
CTD	decreases(expression)			CDK4		D024482
CTD	increases(expression)			CDKN2A		D024482
CTD	decreases(expression)			COL1A1		D024482
CTD	decreases(expression)			IL1B		D024482
CTD	decreases(reaction)			IL1B		D024482
CTD	decreases(response to substance)			IL1B		D024482
CTD	decreases(reaction)			NR1I2		D024482
CTD	increases(activity)			NR1I2		D024482
CTD	decreases(reaction)			PROX1		D024482
CTD	increases(activity)			PROX1		D024482
CTD	increases(expression)			RB1		D024482
CTD	affects(cotreatment)			RXRA		D024482
CTD	decreases(phosphorylation)			RXRA		D024482
CTD	decreases(expression)			TNFSF11		D024482
PubChem	Potency-Replicate_1	uM	10.591	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	16.785	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.439	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	13.333	ESR1	-	GI(Protien) :
PubChem	None	uM		GAPDH	-	GI(Protien) :
PubChem	Potency	uM	23.109	TDP1	-	GI(Protien) :
PubChem	Potency	uM	23.715	TDP1	-	GI(Protien) :
PubChem	Potency	uM	26.609	TDP1	-	GI(Protien) :
ChEMBL	Activity	-		NR1I2	-	Target : CHEMBL3401
ChEMBL	Activity	-		NR1I2	-	Target : CHEMBL3401
ChEMBL	Activity	-		NR1I2	-	Target : CHEMBL3401

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