Tan Lab | DSigDB

Gene Set: D4 : CTD - 2,4,5,2',4',5'-hexachlorobiphenyl

Collection

D4 : CTD

Chemical Name

2,4,5,2',4',5'-hexachlorobiphenyl ( From PubChem : 2,2',4,4',5,5'-HEXACHLOROBIPHENYL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
360.878 g/mol	0	0	7.274	False(3/4)

Structure

InChI

InChI=1S/C12H4Cl6/c13-7-3-11(17)9(15)1-5(7)6-2-10(16)12(18)4-8(6)14/h1-4H

InChIKey

MVWHGTYKUMDIHL-UHFFFAOYSA-N

Links

Gene (208 / 270)

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Source	Type	Gene	Other
CTD	decreases(expression)	ABHD2	C014024
CTD	affects(expression)	ABLIM3	C014024
CTD	decreases(expression)	ACTL7B	C014024
CTD	increases(expression)	ADAM21	C014024
CTD	increases(expression)	ADAMTSL2	C014024
CTD	decreases(expression)	ADAMTSL5	C014024
CTD	decreases(expression)	ADIPOQ	C014024
CTD	affects(activity)	AHR	C014024
CTD	affects(expression)	AKAP12	C014024
CTD	affects(expression)	AKT3	C014024
CTD	affects(expression)	ALDH3B2	C014024
CTD	decreases(expression)	AOC2	C014024
CTD	affects(expression)	AP3B2	C014024
CTD	affects(reaction)	AR	C014024
CTD	increases(activity)	AR	C014024
CTD	affects(cotreatment)	AR	C014024
CTD	decreases(reaction)	AR	C014024
CTD	decreases(reaction)	AR	C014024
CTD	increases(activity)	AR	C014024
CTD	decreases(expression)	ASGR2	C014024
CTD	decreases(expression)	ATG14	C014024
CTD	increases(expression)	ATP6V1C2	C014024
CTD	decreases(expression)	AVIL	C014024
CTD	decreases(expression)	BAK1	C014024
CTD	increases(expression)	BAX	C014024
CTD	affects(expression)	BCAR1	C014024
CTD	decreases(expression)	BCL2	C014024
CTD	affects(expression)	BHLHE40	C014024
CTD	affects(expression)	BMP1	C014024
CTD	decreases(reaction)	BRCA1	C014024
CTD	increases(expression)	BRCA1	C014024
CTD	decreases(expression)	C1QTNF5	C014024
CTD	affects(expression)	CALM1	C014024
CTD	increases(expression)	CASP12	C014024
CTD	increases(reaction)	CASP12	C014024
CTD	increases(expression)	CASP3	C014024
CTD	increases(reaction)	CASP3	C014024
CTD	affects(expression)	CASP8	C014024
CTD	increases(expression)	CASP8	C014024
CTD	increases(expression)	CASP9	C014024
CTD	decreases(expression)	CCDC65	C014024
CTD	increases(expression)	CCL7	C014024
CTD	increases(expression)	CCNA2	C014024
CTD	decreases(expression)	CCND1	C014024
CTD	increases(degradation)	CCND1	C014024
CTD	increases(phosphorylation)	CCND1	C014024
CTD	decreases(reaction)	CCND1	C014024
CTD	decreases(expression)	CD1D	C014024
CTD	affects(expression)	CDC25A	C014024
CTD	increases(expression)	CDCP1	C014024
CTD	decreases(expression)	CEL	C014024
CTD	increases(expression)	CEMIP	C014024
CTD	decreases(expression)	CLEC10A	C014024
CTD	decreases(expression)	CXCL12	C014024
CTD	increases(expression)	CXCL5	C014024
CTD	increases(expression)	CXCL9	C014024
CTD	affects(binding)	CYBB	C014024
CTD	increases(reaction)	CYBB	C014024
CTD	increases(expression)	CYCS	C014024
CTD	increases(reaction)	CYCS	C014024
CTD	increases(expression)	CYP11B2	C014024
CTD	decreases(expression)	CYP19A1	C014024
CTD	increases(expression)	CYP19A1	C014024
CTD	affects(expression)	CYP1A1	C014024
CTD	increases(activity)	CYP1A2	C014024
CTD	affects(expression)	CYP1B1	C014024
CTD	increases(expression)	CYP3A4	C014024
CTD	affects(cotreatment)	DAPK1	C014024
CTD	increases(expression)	DAPK1	C014024
CTD	increases(expression)	DCSTAMP	C014024
CTD	decreases(expression)	DEPDC7	C014024
CTD	decreases(expression)	DHX40	C014024
CTD	decreases(expression)	DOCK7	C014024
CTD	affects(expression)	DTYMK	C014024
CTD	decreases(expression)	DUSP9	C014024
CTD	affects(expression)	E2F7	C014024
CTD	decreases(expression)	EFCC1	C014024
CTD	affects(localization)	EGFR	C014024
CTD	increases(phosphorylation)	EGFR	C014024
CTD	affects(binding)	ESR1	C014024
CTD	decreases(expression)	ESR2	C014024
CTD	decreases(expression)	FABP4	C014024
CTD	affects(expression)	FBXL2	C014024
CTD	decreases(expression)	FBXO24	C014024
CTD	decreases(expression)	FCGR2B	C014024
CTD	affects(expression)	FOS	C014024
CTD	decreases(reaction)	FOXO3	C014024
CTD	increases(phosphorylation)	FOXO3	C014024
CTD	decreases(phosphorylation)	FOXO3	C014024
CTD	decreases(expression)	FZD9	C014024
CTD	affects(expression)	GAB1	C014024
CTD	affects(binding)	GABRA1	C014024
CTD	decreases(reaction)	GABRA1	C014024
CTD	increases(activity)	GABRA1	C014024
CTD	affects(binding)	GABRB2	C014024
CTD	decreases(reaction)	GABRB2	C014024
CTD	increases(activity)	GABRB2	C014024
CTD	affects(binding)	GABRG2	C014024
CTD	decreases(reaction)	GABRG2	C014024
CTD	increases(activity)	GABRG2	C014024
CTD	decreases(expression)	GGTA1P	C014024
CTD	affects(cotreatment)	GJA1	C014024
CTD	decreases(expression)	GJA1	C014024
CTD	affects(expression)	GJC1	C014024
CTD	affects(expression)	GRM3	C014024
CTD	decreases(phosphorylation)	GSK3B	C014024
CTD	increases(expression)	GYPE	C014024
CTD	decreases(expression)	HBG1	C014024
CTD	decreases(expression)	HIST1H1B	C014024
CTD	decreases(expression)	HIST2H2AB	C014024
CTD	increases(expression)	HK2	C014024
CTD	decreases(expression)	HKDC1	C014024
CTD	affects(expression)	HLA-DQA1	C014024
CTD	decreases(expression)	HOXB9	C014024
CTD	increases(expression)	HRH1	C014024
CTD	affects(expression)	HS6ST1	C014024
CTD	decreases(expression)	HSD11B2	C014024
CTD	affects(expression)	HSPA1B	C014024
CTD	increases(expression)	ICAM1	C014024
CTD	increases(expression)	ICAM1	C014024
CTD	decreases(reaction)	ICAM1	C014024
CTD	increases(expression)	IFIT1	C014024
CTD	decreases(expression)	IFNG	C014024
CTD	affects(expression)	IGFBP2	C014024
CTD	affects(expression)	IGFBP3	C014024
CTD	decreases(expression)	IGFBP3	C014024
CTD	decreases(expression)	IL10	C014024
CTD	decreases(expression)	IL1B	C014024
CTD	increases(expression)	IL1R2	C014024
CTD	increases(expression)	IL1RN	C014024
CTD	increases(expression)	INHBA	C014024
CTD	decreases(expression)	IQCD	C014024
CTD	affects(expression)	ITGB4	C014024
CTD	affects(expression)	ITGB8	C014024
CTD	increases(phosphorylation)	JAK1	C014024
CTD	decreases(reaction)	JAK1	C014024
CTD	affects(expression)	JUN	C014024
CTD	affects(expression)	KLF10	C014024
CTD	decreases(expression)	LRIT1	C014024
CTD	affects(expression)	LTA	C014024
CTD	decreases(expression)	LTB4R2	C014024
CTD	decreases(expression)	MAGEE1	C014024
CTD	decreases(expression)	MAN2A1	C014024
CTD	affects(binding)	MAPK1	C014024
CTD	increases(activity)	MAPK1	C014024
CTD	decreases(reaction)	MAPK1	C014024
CTD	increases(phosphorylation)	MAPK1	C014024
CTD	decreases(phosphorylation)	MAPK1	C014024
CTD	affects(binding)	MAPK3	C014024
CTD	increases(activity)	MAPK3	C014024
CTD	decreases(reaction)	MAPK3	C014024
CTD	increases(phosphorylation)	MAPK3	C014024
CTD	decreases(phosphorylation)	MAPK3	C014024
CTD	decreases(expression)	MDFI	C014024
CTD	decreases(reaction)	MDM2	C014024
CTD	increases(phosphorylation)	MDM2	C014024
CTD	increases(phosphorylation)	MDM2	C014024
CTD	decreases(expression)	MEIS1	C014024
CTD	decreases(expression)	MESP1	C014024
CTD	increases(expression)	MET	C014024
CTD	decreases(expression)	MMP11	C014024
CTD	increases(expression)	MMP7	C014024
CTD	decreases(expression)	MS4A6A	C014024
CTD	affects(expression)	MT1F	C014024
CTD	affects(expression)	MT1G	C014024
CTD	increases(expression)	MT1M	C014024
CTD	affects(expression)	MT1X	C014024
CTD	affects(expression)	MVK	C014024
CTD	increases(expression)	MX1	C014024
CTD	affects(localization)	NCF1	C014024
CTD	affects(binding)	NCF1	C014024
CTD	increases(reaction)	NCF1	C014024
CTD	increases(localization)	NCF1	C014024
CTD	increases(phosphorylation)	NCF1	C014024
CTD	decreases(reaction)	NCF1	C014024
CTD	increases(phosphorylation)	NCF1	C014024
CTD	affects(expression)	NDRG1	C014024
CTD	affects(binding)	NR1I2	C014024
CTD	increases(activity)	NR1I2	C014024
CTD	increases(activity)	NR1I2	C014024
CTD	increases(expression)	NR1I2	C014024
CTD	increases(expression)	NR1I3	C014024
CTD	decreases(reaction)	NR3C1	C014024
CTD	increases(activity)	NR3C1	C014024
CTD	decreases(expression)	NRG1	C014024
CTD	increases(expression)	OAS3	C014024
CTD	decreases(expression)	OCLN	C014024
CTD	increases(activity)	PARP1	C014024
CTD	decreases(expression)	PKIB	C014024
CTD	increases(expression)	PRAP1	C014024
CTD	increases(expression)	PSD3	C014024
CTD	increases(expression)	PTGER1	C014024
CTD	affects(expression)	QSOX1	C014024
CTD	increases(phosphorylation)	RAC1	C014024
CTD	decreases(activity)	RAF1	C014024
CTD	increases(phosphorylation)	RAF1	C014024
CTD	increases(reaction)	RAF1	C014024
CTD	decreases(expression)	RASL10B	C014024
CTD	affects(expression)	RCBTB1	C014024
CTD	increases(expression)	RHO	C014024
CTD	affects(expression)	RHOB	C014024
CTD	decreases(expression)	RNF207	C014024
CTD	decreases(expression)	RPGRIP1	C014024
CTD	decreases(expression)	RPRD1B	C014024
CTD	increases(expression)	RSAD2	C014024
CTD	affects(expression)	SAMD9L	C014024
CTD	decreases(expression)	SCAMP5	C014024
CTD	increases(expression)	SCG5	C014024
CTD	decreases(expression)	SEMA6A	C014024
CTD	decreases(expression)	SEPP1	C014024
CTD	increases(expression)	SGOL1	C014024
CTD	affects(expression)	SIX4	C014024
CTD	decreases(expression)	SIX5	C014024
CTD	affects(expression)	SLC16A6	C014024
CTD	increases(expression)	SLC1A3	C014024
CTD	affects(expression)	SLC51B	C014024
CTD	increases(expression)	SLC6A4	C014024
CTD	increases(expression)	SLC8A3	C014024
CTD	decreases(expression)	SNX16	C014024
CTD	increases(expression)	SPP1	C014024
CTD	increases(phosphorylation)	SRC	C014024
CTD	decreases(reaction)	SRC	C014024
CTD	increases(expression)	SRF	C014024
CTD	decreases(expression)	SYMPK	C014024
CTD	affects(expression)	TAX1BP3	C014024
CTD	affects(expression)	TCEA2	C014024
CTD	increases(expression)	TCF15	C014024
CTD	decreases(expression)	TENM3	C014024
CTD	increases(expression)	TFPI2	C014024
CTD	decreases(expression)	TJP1	C014024
CTD	decreases(reaction)	TJP1	C014024
CTD	increases(expression)	TKTL1	C014024
CTD	decreases(expression)	TLR6	C014024
CTD	increases(expression)	TM4SF19	C014024
CTD	increases(expression)	TMEM158	C014024
CTD	increases(expression)	TMEM229A	C014024
CTD	decreases(expression)	TMEM37	C014024
CTD	decreases(expression)	TNF	C014024
CTD	increases(expression)	TNFRSF11B	C014024
CTD	affects(expression)	TNFSF10	C014024
CTD	affects(expression)	TNS4	C014024
CTD	affects(expression)	TOR1A	C014024
CTD	increases(expression)	TP53	C014024
CTD	increases(phosphorylation)	TP53	C014024
CTD	increases(reaction)	TP53	C014024
CTD	decreases(expression)	TRAM2	C014024
CTD	decreases(expression)	TRHR	C014024
CTD	decreases(reaction)	TRHR	C014024
CTD	decreases(expression)	TSHR	C014024
CTD	decreases(expression)	TTC23	C014024
CTD	affects(binding)	TTR	C014024
CTD	decreases(reaction)	TTR	C014024
CTD	decreases(expression)	TUB	C014024
CTD	increases(expression)	TUBB3	C014024
CTD	affects(expression)	TXNIP	C014024
CTD	increases(phosphorylation)	TYK2	C014024
CTD	decreases(expression)	UNC5B	C014024
CTD	decreases(expression)	VCAM1	C014024
CTD	increases(expression)	VCAM1	C014024
CTD	decreases(reaction)	VCAM1	C014024
CTD	decreases(expression)	WNT5A	C014024
CTD	affects(cotreatment)	XRCC1	C014024
CTD	decreases(expression)	XRCC1	C014024
CTD	affects(cotreatment)	XRCC3	C014024
CTD	increases(expression)	XRCC3	C014024
CTD	decreases(expression)	ZADH2	C014024
CTD	affects(expression)	ZFP36L1	C014024
CTD	affects(expression)	ZNF672	C014024
CTD	decreases(expression)	ZNF697	C014024
CTD	decreases(expression)	ZNF784	C014024

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