Tan Lab | DSigDB

Gene Set: D4 : CTD - Glutathione Disulfide

Collection

D4 : CTD

Chemical Name

Glutathione Disulfide ( From PubChem : OXIGLUTATIONE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
612.631 g/mol	10	20	-0.9126	False(1/4)

Structure

InChI

InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1

InChIKey

YPZRWBKMTBYPTK-BJDJZHNGSA-N

Links

Gene (9 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(export)			ABCC1		D019803
CTD	decreases(reaction)			ABCC1		D019803
CTD	increases(reaction)			ABCC1		D019803
CTD	increases(transport)			ABCC1		D019803
CTD	affects(binding)			ABCC1		D019803
CTD	increases(reaction)			ABCC1		D019803
CTD	increases(expression)			CDKN1A		D019803
CTD	decreases(activity)			CFTR		D019803
CTD	decreases(activity)			GSR		D019803
CTD	decreases(reaction)			GSR		D019803
CTD	increases(activity)			HIF1A		D019803
CTD	increases(reaction)			HIF1A		D019803
CTD	increases(abundance)			SOD2		D019803
CTD	decreases(reaction)			TP53		D019803
CTD	increases(glutathionylation)			TP53		D019803
CTD	increases(activity)			TP53		D019803
CTD	increases(expression)			TP53		D019803
CTD	increases(phosphorylation)			TP53		D019803
PubChem	Potency-Replicate_1	uM	0.013	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.058	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.060	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.371	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.562	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	14.507	ESR1	-	GI(Protien) :

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