Tan Lab | DSigDB

Gene Set: D4 : CTD - Citric Acid

Collection

D4 : CTD

Chemical Name

Citric Acid ( From PubChem : CITRIC ACID )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Approved	Not	Approved	Approved	Approved	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
192.124 g/mol	4	7	-1.2485	True

Structure

InChI

InChI=1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChIKey

KRKNYBCHXYNGOX-UHFFFAOYSA-N

Links

Gene (22 / 44)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			ACO2		D019343
CTD	decreases(activity)			ACO2		D019343
CTD	affects(cotreatment)			BAX		D019343
CTD	increases(expression)			BAX		D019343
CTD	affects(cotreatment)			BCL2		D019343
CTD	decreases(expression)			BCL2		D019343
CTD	affects(cotreatment)			BCL2L1		D019343
CTD	decreases(expression)			BCL2L1		D019343
CTD	affects(cotreatment)			CASP12		D019343
CTD	increases(activity)			CASP12		D019343
CTD	affects(cotreatment)			CASP3		D019343
CTD	increases(activity)			CASP3		D019343
CTD	affects(cotreatment)			CDKN1A		D019343
CTD	increases(expression)			CDKN1A		D019343
CTD	affects(binding)			GLUD1		D019343
CTD	decreases(activity)			GLUD1		D019343
CTD	decreases(reaction)			GLUD1		D019343
CTD	increases(activity)			KLK5		D019343
CTD	increases(reaction)			MUC5AC		D019343
CTD	increases(secretion)			MUC5AC		D019343
CTD	decreases(reaction)			MUC5AC		D019343
CTD	increases(reaction)			SLC13A2		D019343
CTD	increases(uptake)			SLC13A2		D019343
CTD	affects(cotreatment)			TERT		D019343
CTD	decreases(activity)			TERT		D019343
CTD	affects(binding)			TF		D019343
CTD	increases(reaction)			TF		D019343
CTD	decreases(reaction)			TRPV1		D019343
CTD	increases(activity)			TRPV1		D019343
CTD	affects(binding)			VEGFA		D019343
PubChem	IC50	uM	3.545	ABHD5	-	GI(Protien) :
PubChem	IC50	uM	5.632	ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	Potency	uM	12.589	ALDH1A1	-	GI(Protien) :
PubChem	None	uM		HNF4A	-	GI(Protien) :
PubChem	Potency	uM	54.483	NFE2L2	-	GI(Protien) :
PubChem	IC50	uM	3.708	PLIN1	-	GI(Protien) :
PubChem	IC50	uM	3.545	PLIN5	-	GI(Protien) :
PubChem	IC50	uM	5.632	PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
ChEMBL	Potency	nM	12589.300	ALDH1A1	-	Target : CHEMBL3577
ChEMBL	Potency	nM	79432.800	KDM4A	-	Target : CHEMBL5896

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