Tan Lab | DSigDB

Gene Set: D4 : CTD - Lamivudine

Collection

D4 : CTD

Chemical Name

Lamivudine ( From PubChem : LAMIVUDINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
229.256 g/mol	2	7	-0.0129	True

Structure

InChI

InChI=1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1

InChIKey

JTEGQNOMFQHVDC-NKWVEPMBSA-N

Links

Gene (74 / 137)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(expression)		ACTA2		D019259
CTD	affects(cotreatment)		AFAP1		D019259
CTD	decreases(expression)		AFAP1		D019259
CTD	affects(binding)		ALB		D019259
CTD	affects(cotreatment)		ASNS		D019259
CTD	increases(expression)		ASNS		D019259
CTD	affects(cotreatment)		ASS1		D019259
CTD	increases(expression)		ASS1		D019259
CTD	affects(cotreatment)		ATF3		D019259
CTD	increases(expression)		ATF3		D019259
CTD	increases(expression)		BNIP3L		D019259
CTD	affects(cotreatment)		CARS		D019259
CTD	increases(expression)		CARS		D019259
CTD	affects(cotreatment)		CASP5		D019259
CTD	increases(expression)		CASP5		D019259
CTD	decreases(expression)		CCNA2		D019259
CTD	affects(cotreatment)		CCNA2		D019259
CTD	affects(cotreatment)		CCNC		D019259
CTD	decreases(expression)		CCNC		D019259
CTD	affects(cotreatment)		CCND1		D019259
CTD	increases(expression)		CCND1		D019259
CTD	decreases(expression)		CCND2		D019259
CTD	affects(cotreatment)		CCND2		D019259
CTD	decreases(expression)		CCNE2		D019259
CTD	affects(cotreatment)		CCNE2		D019259
CTD	affects(cotreatment)		CD44		D019259
CTD	increases(expression)		CD44		D019259
CTD	affects(cotreatment)		CD83		D019259
CTD	decreases(expression)		CD83		D019259
CTD	affects(cotreatment)		CDK7		D019259
CTD	increases(expression)		CDK7		D019259
CTD	decreases(expression)		CDKN1A		D019259
CTD	affects(cotreatment)		CDKN1A		D019259
CTD	affects(cotreatment)		CDKN1B		D019259
CTD	decreases(expression)		CDKN1B		D019259
CTD	affects(cotreatment)		CDKN1C		D019259
CTD	decreases(expression)		CDKN1C		D019259
CTD	affects(cotreatment)		CDKN2C		D019259
CTD	decreases(expression)		CDKN2C		D019259
CTD	decreases(expression)		COL3A1		D019259
CTD	affects(cotreatment)		COMT		D019259
CTD	increases(expression)		COMT		D019259
CTD	increases(activity)		DCK		D019259
CTD	increases(phosphorylation)		DCK		D019259
CTD	increases(expression)		DDIT3		D019259
CTD	affects(cotreatment)		DDIT3		D019259
CTD	affects(cotreatment)		DHFR		D019259
CTD	decreases(expression)		DHFR		D019259
CTD	decreases(reaction)		EDN1		D019259
CTD	increases(secretion)		EDN1		D019259
CTD	affects(cotreatment)		EIF4EBP1		D019259
CTD	increases(expression)		EIF4EBP1		D019259
CTD	affects(cotreatment)		FAM129A		D019259
CTD	increases(expression)		FAM129A		D019259
CTD	affects(cotreatment)		GARS		D019259
CTD	increases(expression)		GARS		D019259
CTD	affects(cotreatment)		GAS1		D019259
CTD	decreases(expression)		GAS1		D019259
CTD	affects(cotreatment)		GYPA		D019259
CTD	increases(mutagenesis)		GYPA		D019259
CTD	affects(cotreatment)		HAX1		D019259
CTD	increases(expression)		HAX1		D019259
CTD	affects(cotreatment)		IFNA2		D019259
CTD	increases(expression)		IFNA2		D019259
CTD	increases(expression)		IFNG		D019259
CTD	affects(cotreatment)		IL27RA		D019259
CTD	increases(expression)		IL27RA		D019259
CTD	affects(cotreatment)		KCNG1		D019259
CTD	increases(expression)		KCNG1		D019259
CTD	affects(cotreatment)		KLF4		D019259
CTD	increases(expression)		KLF4		D019259
CTD	affects(cotreatment)		KRT7		D019259
CTD	increases(expression)		KRT7		D019259
CTD	affects(cotreatment)		KYNU		D019259
CTD	increases(expression)		KYNU		D019259
CTD	affects(cotreatment)		LAMB3		D019259
CTD	increases(expression)		LAMB3		D019259
CTD	affects(cotreatment)		MARS		D019259
CTD	increases(expression)		MARS		D019259
CTD	increases(expression)		MMP1		D019259
CTD	affects(cotreatment)		MTHFD2		D019259
CTD	increases(expression)		MTHFD2		D019259
CTD	decreases(phosphorylation)		NOS3		D019259
CTD	decreases(reaction)		NOS3		D019259
CTD	affects(cotreatment)		OGT		D019259
CTD	increases(expression)		OGT		D019259
CTD	affects(cotreatment)		PCK2		D019259
CTD	increases(expression)		PCK2		D019259
CTD	affects(cotreatment)		PSAT1		D019259
CTD	increases(expression)		PSAT1		D019259
CTD	affects(cotreatment)		RABEPK		D019259
CTD	increases(expression)		RABEPK		D019259
CTD	affects(cotreatment)		RBL1		D019259
CTD	decreases(expression)		RBL1		D019259
CTD	affects(cotreatment)		RBL2		D019259
CTD	decreases(expression)		RBL2		D019259
CTD	affects(cotreatment)		RIPK2		D019259
CTD	increases(expression)		RIPK2		D019259
CTD	affects(cotreatment)		SLC1A4		D019259
CTD	increases(expression)		SLC1A4		D019259
CTD	affects(cotreatment)		SLC1A5		D019259
CTD	increases(expression)		SLC1A5		D019259
CTD	increases(uptake)		SLC22A1		D019259
CTD	increases(uptake)		SLC22A2		D019259
CTD	increases(uptake)		SLC22A3		D019259
CTD	affects(cotreatment)		SLC25A19		D019259
CTD	affects(response to substance)		SLC25A19		D019259
CTD	decreases(reaction)		SLC28A1		D019259
CTD	increases(transport)		SLC28A1		D019259
CTD	affects(cotreatment)		SLC31A1		D019259
CTD	increases(expression)		SLC31A1		D019259
CTD	affects(cotreatment)		SLC3A2		D019259
CTD	increases(expression)		SLC3A2		D019259
CTD	affects(cotreatment)		SLC6A4		D019259
CTD	increases(expression)		SLC6A4		D019259
CTD	increases(reaction)		SLC6A4		D019259
CTD	increases(uptake)		SLC6A4		D019259
CTD	increases(activity)		SLC6A4		D019259
CTD	affects(cotreatment)		STC2		D019259
CTD	increases(expression)		STC2		D019259
CTD	affects(cotreatment)		TCEA1		D019259
CTD	increases(expression)		TCEA1		D019259
CTD	decreases(expression)		TGFB1		D019259
CTD	decreases(expression)		TIMP1		D019259
CTD	affects(cotreatment)		TRIB3		D019259
CTD	increases(expression)		TRIB3		D019259
CTD	affects(cotreatment)		TYMS		D019259
CTD	decreases(expression)		TYMS		D019259
CTD	affects(cotreatment)		TYRP1		D019259
CTD	decreases(expression)		TYRP1		D019259
CTD	affects(cotreatment)		WARS		D019259
CTD	increases(expression)		WARS		D019259
CTD	affects(cotreatment)		YARS		D019259
CTD	increases(expression)		YARS		D019259
ChEMBL	Activity	-	ABCC1	-	Target : CHEMBL3004
ChEMBL	Activity	-	ABCC2	-	Target : CHEMBL5748
ChEMBL	Activity	-	ABCC3	-	Target : CHEMBL5918

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