Tan Lab | DSigDB

Gene Set: D4 : CTD - Quinpirole

Collection

D4 : CTD

Chemical Name

Quinpirole ( From PubChem : QUINPIROLE DIHYDROCHLORIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
219.326 g/mol	1	2	1.9368	True

Structure

InChI

InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1

InChIKey

Links

Gene (10 / 30)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			DRD2		D019257
CTD	decreases(reaction)			DRD2		D019257
CTD	increases(abundance)			DRD2		D019257
CTD	increases(activity)			DRD2		D019257
CTD	affects(binding)			DRD2		D019257
CTD	decreases(reaction)			DRD2		D019257
CTD	increases(activity)			DRD2		D019257
CTD	affects(binding)			DRD2		D019257
CTD	decreases(transport)			DRD2		D019257
CTD	increases(activity)			DRD2		D019257
CTD	decreases(reaction)			DRD2		D019257
CTD	affects(binding)			DRD3		D019257
CTD	increases(activity)			DRD3		D019257
CTD	affects(localization)			SLC6A3		D019257
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2A		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	None	uM		HTR2C		GI(Protien) :
PubChem	Potency	uM	35.481	THRB	-	GI(Protien) :
PubChem	Potency	uM	25.119	EHMT2	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
ChEMBL	Activity	-		DRD2	-	Target : CHEMBL217
ChEMBL	Activity	-		DRD2	-	Target : CHEMBL217
ChEMBL	Activity	-		DRD2	-	Target : CHEMBL217
ChEMBL	Activity	-		DRD3	-	Target : CHEMBL234
ChEMBL	Potency	nM	25118.900	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	281.800	TDP1	-	Target : CHEMBL1075138
ChEMBL	Potency	nM	35481.300	THRB	-	Target : CHEMBL1947

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