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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - N-Methyl-3,4-methylenedioxyamphetamine

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Collection	D4 : CTD
Chemical Name	N-Methyl-3,4-methylenedioxyamphetamine ( From PubChem : MDMA )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not 1
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 193.242 g/mol 1 3 1.9566 True
Structure
InChI	InChI=1S/C11H15NO2/c1-8(12-2)5-9-3-4-10-11(6-9)14-7-13-10/h3-4,6,8,12H,5,7H2,1-2H3/t8-/m1/s1
InChIKey	SHXWCVYOXRDMCX-MRVPVSSYSA-N
Links
Gene (25 / 60) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(activity) ABCB1 D018817 CTD increases(expression) BAD D018817 CTD affects(cotreatment) BAK1 D018817 CTD increases(expression) BAK1 D018817 CTD affects(cotreatment) BAX D018817 CTD increases(expression) BAX D018817 CTD affects(cotreatment) BBC3 D018817 CTD increases(expression) BBC3 D018817 CTD affects(cotreatment) BCL2 D018817 CTD decreases(expression) BCL2 D018817 CTD affects(cotreatment) BCL2L1 D018817 CTD decreases(expression) BCL2L1 D018817 CTD affects(cotreatment) BCL2L11 D018817 CTD increases(expression) BCL2L11 D018817 CTD affects(cotreatment) BID D018817 CTD increases(expression) BID D018817 CTD decreases(abundance) CAT D018817 CTD decreases(reaction) CAT D018817 CTD affects(cotreatment) CHRNA4 D018817 CTD decreases(reaction) CHRNA4 D018817 CTD increases(activity) CHRNA4 D018817 CTD increases(activity) CHRNA7 D018817 CTD increases(reaction) CHRNA7 D018817 CTD decreases(reaction) CHRNA7 D018817 CTD affects(cotreatment) CHRNB2 D018817 CTD decreases(reaction) CHRNB2 D018817 CTD increases(activity) CHRNB2 D018817 CTD decreases(activity) CYP1A2 D018817 CTD increases(metabolic processing) CYP2D6 D018817 CTD decreases(reaction) CYP2D6 D018817 CTD increases(metabolic processing) CYP2D6 D018817 CTD decreases(activity) CYP2D6 D018817 CTD decreases(reaction) CYP3A4 D018817 CTD increases(expression) CYP3A4 D018817 CTD increases(reaction) CYP3A4 D018817 CTD decreases(activity) CYP3A4 D018817 CTD increases(activity) F3 D018817 CTD increases(reaction) F3 D018817 CTD increases(expression) F3 D018817 CTD affects(binding) GABRA1 D018817 CTD decreases(activity) GABRA1 D018817 CTD affects(binding) GABRB2 D018817 CTD decreases(activity) GABRB2 D018817 CTD affects(binding) GABRG2 D018817 CTD decreases(activity) GABRG2 D018817 CTD decreases(reaction) NR1I2 D018817 CTD increases(expression) NR1I2 D018817 CTD increases(reaction) NR1I2 D018817 CTD affects(reaction) SLC16A1 D018817 CTD increases(uptake) SLC16A1 D018817 CTD increases(expression) SLC16A1 D018817 CTD affects(expression) SLC6A4 D018817 CTD affects(binding) SLC6A4 D018817 CTD affects(reaction) SLC6A4 D018817 CTD affects(binding) SLC6A4 D018817 CTD decreases(expression) SLC6A4 D018817 CTD affects(response to substance) SOD1 D018817 CTD increases(activity) TNF D018817 CTD increases(reaction) TNF D018817 CTD increases(expression) TNF D018817
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