Tan Lab | DSigDB

Gene Set: D4 : CTD - Stavudine

Collection

D4 : CTD

Chemical Name

Stavudine ( From PubChem : STAVUDINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
224.213 g/mol	2	5	-0.7091	True

Structure

InChI

InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1

InChIKey

Links

Gene (24 / 27)

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Source	Type	Unit	Gene	PMID	Other
CTD	increases(expression)		ABCB1		D018119
CTD	decreases(expression)		ADIPOQ		D018119
CTD	affects(binding)		ALB		D018119
CTD	decreases(expression)		BCL2		D018119
CTD	increases(expression)		CCL2		D018119
CTD	affects(cotreatment)		HFE		D018119
CTD	affects(response to substance)		HFE		D018119
CTD	increases(expression)		IL1B		D018119
CTD	increases(expression)		IL6		D018119
CTD	decreases(expression)		LEP		D018119
CTD	decreases(expression)		PPARG		D018119
CTD	affects(cotreatment)		SLC25A19		D018119
CTD	affects(response to substance)		SLC25A19		D018119
CTD	affects(transport)		SLC29A3		D018119
CTD	increases(expression)		TNF		D018119
CTD	increases(expression)		TYMP		D018119
CTD	increases(expression)		UCP1		D018119
CTD	decreases(expression)		UCP2		D018119
CTD	decreases(expression)		UCP3		D018119
PubChem	None	uM	MRGPRX1	-	GI(Protien) :
PubChem	None	uM	NR2F2	-	GI(Protien) :
ChEMBL	Inhibition	-	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-	CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-	CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-	CYP3A4	-	Target : CHEMBL340

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