Tan Lab | DSigDB

Gene Set: D4 : CTD - gamma-Linolenic Acid

Collection

D4 : CTD

Chemical Name

gamma-Linolenic Acid ( From PubChem : 506-26-3 )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
278.43 g/mol	1	2	5.6605	False(3/4)

Structure

InChI

InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)/b7-6+,10-9+,13-12+

InChIKey

VZCCETWTMQHEPK-YHTMAJSVSA-N

Links

Gene (50 / 67)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			AKR1C1		D017965
CTD	increases(expression)			AKR1C4		D017965
CTD	decreases(expression)			APOH		D017965
CTD	decreases(reaction)			AR		D017965
CTD	increases(activity)			AR		D017965
CTD	increases(expression)			ASAH1		D017965
CTD	increases(activity)			CASP3		D017965
CTD	decreases(expression)			CCNA2		D017965
CTD	decreases(expression)			CCNE1		D017965
CTD	decreases(expression)			CDK1		D017965
CTD	affects(cotreatment)			CLDN5		D017965
CTD	increases(expression)			CLDN5		D017965
CTD	increases(localization)			CLDN5		D017965
CTD	increases(expression)			CLTA		D017965
CTD	increases(expression)			FTH1		D017965
CTD	increases(activity)			GCLC		D017965
CTD	increases(expression)			GCLC		D017965
CTD	increases(expression)			GRK5		D017965
CTD	increases(expression)			HEXB		D017965
CTD	decreases(expression)			HIST1H2AC		D017965
CTD	increases(expression)			HMOX1		D017965
CTD	increases(expression)			HMOX1		D017965
CTD	affects(expression)			IL2		D017965
CTD	decreases(expression)			JUNB		D017965
CTD	decreases(expression)			KYNU		D017965
CTD	decreases(expression)			MAPK3		D017965
CTD	decreases(expression)			MMP11		D017965
CTD	increases(expression)			MT1G		D017965
CTD	increases(expression)			MT1L		D017965
CTD	decreases(expression)			MYC		D017965
CTD	affects(cotreatment)			OCLN		D017965
CTD	increases(expression)			OCLN		D017965
CTD	increases(localization)			OCLN		D017965
CTD	decreases(expression)			PCNA		D017965
CTD	decreases(expression)			PDLIM1		D017965
CTD	increases(expression)			PLIN2		D017965
CTD	affects(binding)			PPARA		D017965
CTD	increases(activity)			PPARA		D017965
CTD	affects(binding)			PPARG		D017965
CTD	increases(activity)			PPARG		D017965
CTD	increases(expression)			PTGR1		D017965
CTD	increases(expression)			PTGS2		D017965
CTD	increases(expression)			S100P		D017965
CTD	decreases(expression)			SKP2		D017965
CTD	increases(expression)			SLC3A2		D017965
CTD	increases(expression)			ST13		D017965
CTD	decreases(expression)			TFF3		D017965
CTD	affects(cotreatment)			TJP1		D017965
CTD	increases(expression)			TJP1		D017965
CTD	increases(localization)			TJP1		D017965
CTD	decreases(expression)			TNF		D017965
CTD	increases(expression)			TXN		D017965
CTD	increases(expression)			TXNRD1		D017965
PubChem	AC50_uM	uM	0.505	CASP6	-	GI(Protien) :
PubChem	None	uM		CASP6	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	14.125	KAT2A	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
PubChem	Potency	uM	19.953	POLH	-	GI(Protien) :
PubChem	Potency	uM	30.131	POLH	-	GI(Protien) :
PubChem	Potency	uM	39.811	POLI	-	GI(Protien) :
PubChem	Potency	uM	67.016	POLI	-	GI(Protien) :
PubChem	Potency	uM	21.192	POLK		GI(Protien) :
PubChem	Potency	uM	23.778	POLK	-	GI(Protien) :
PubChem	Potency	uM	50.119	POLK	-	GI(Protien) :
PubChem	Potency	uM	39.811	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	14125.400	KAT2A	-	Target : CHEMBL5501

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