Tan Lab | DSigDB

Gene Set: D4 : CTD - rimexolone

Collection

D4 : CTD

Chemical Name

rimexolone ( From PubChem : VEXOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
370.525 g/mol	1	3	4.4965	True

Structure

InChI

InChI=1S/C24H34O3/c1-6-20(27)24(5)14(2)11-18-17-8-7-15-12-16(25)9-10-22(15,3)21(17)19(26)13-23(18,24)4/h9-10,12,14,17-19,21,26H,6-8,11,13H2,1-5H3/t14-,17-,18-,19+,21-,22+,23+,24-/m1/s1

InChIKey

QTTRZHGPGKRAFB-WEGHLOLESA-N

Links

Gene (9 / 21)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			CD28		C013769
CTD	decreases(reaction)			CD28		C013769
CTD	increases(expression)			CD28		C013769
CTD	increases(secretion)			CD28		C013769
CTD	decreases(expression)			CD4		C013769
CTD	decreases(reaction)			CD4		C013769
CTD	decreases(reaction)			IFNG		C013769
CTD	increases(secretion)			IFNG		C013769
CTD	decreases(reaction)			IL2		C013769
CTD	increases(secretion)			IL2		C013769
CTD	affects(cotreatment)			NFKBIA		C013769
CTD	decreases(reaction)			NFKBIA		C013769
CTD	increases(expression)			NFKBIA		C013769
CTD	decreases(reaction)			TNF		C013769
CTD	increases(secretion)			TNF		C013769
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	Potency	uM	0.016	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	0.018	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	12.995	TDP1	-	GI(Protien) :
PubChem	Potency	uM	16.360	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	16.400	NFE2L2	-	Target : CHEMBL1075094

Download gene sets

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