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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 8-Hydroxy-2-(di-n-propylamino)tetralin

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Collection	D4 : CTD
Chemical Name	8-Hydroxy-2-(di-n-propylamino)tetralin ( From PubChem : 8-OH-DPAT )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 247.376 g/mol 1 2 3.3715 True
Structure
InChI	InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3/t14-/m0/s1
InChIKey	ASXGJMSKWNBENU-AWEZNQCLSA-N
Links
Gene (17 / 48) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(reaction) CXCL8 D017371 CTD increases(secretion) CXCL8 D017371 CTD affects(binding) HTR1A D017371 CTD increases(activity) HTR1A D017371 CTD affects(binding) HTR1A D017371 CTD decreases(reaction) HTR1A D017371 CTD increases(activity) HTR1A D017371 CTD affects(binding) HTR7 D017371 CTD increases(activity) HTR7 D017371 CTD increases(reaction) IL12B D017371 CTD increases(secretion) IL12B D017371 CTD increases(reaction) IL1B D017371 CTD increases(secretion) IL1B D017371 CTD increases(reaction) IL6 D017371 CTD increases(secretion) IL6 D017371 CTD decreases(reaction) TNF D017371 CTD increases(secretion) TNF D017371 PubChem Potency uM 23.778 EHMT2 - GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1A GI(Protien) : PubChem None uM HTR1B GI(Protien) : PubChem None uM HTR1B GI(Protien) : PubChem None uM HTR1D GI(Protien) : PubChem None uM HTR1D GI(Protien) : PubChem None uM HTR1D GI(Protien) : PubChem None uM HTR1D GI(Protien) : PubChem None uM HTR1E GI(Protien) : PubChem None uM HTR1E GI(Protien) : PubChem None uM HTR1F GI(Protien) : PubChem None uM HTR2A GI(Protien) : PubChem None uM HTR2B GI(Protien) : PubChem None uM HTR2C GI(Protien) : PubChem None uM HTR5A GI(Protien) : PubChem None uM HTR5A GI(Protien) : PubChem None uM HTR7 GI(Protien) : PubChem None uM HTR7 GI(Protien) : PubChem None uM HTR7 GI(Protien) : PubChem None uM HTR7 GI(Protien) : ChEMBL Potency nM 23778.100 EHMT2 - Target : CHEMBL6032 ChEMBL Inhibition - AKT1 - Target : CHEMBL4282
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