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Gene Set: D4 : CTD - Isradipine

Collection D4 : CTD
Chemical Name Isradipine ( From PubChem : ISRADIPINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
ApprovedNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
371.387 g/mol 1 8 2.911 True
Structure
InChI InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3/t16-/m1/s1
InChIKey HMJIYCCIJYRONP-MRXNPFEDSA-N
Links

Gene (8 / 14)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(reaction)ABCB11
D017275
CTDincreases(transport)ABCB11
D017275
CTDdecreases(activity)ABCB11
D017275
CTDaffects(metabolic processing)CYP3A4
D017275
CTDincreases(secretion)FGF2
D017275
CTDincreases(activity)REN
D017275
PubChem AhR Potency (uM)uMAHR-GI(Protien) :
PubChem NoneuMAPAF1-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM10.000CYP3A4-GI(Protien) :
PubChem NoneuMCYP3A4-GI(Protien) :
PubChem PotencyuM12.589NPSR1-GI(Protien) :
ChEMBLPotencynM10000.000CYP3A4
-Target : CHEMBL340
ChEMBLAC50nM10000.000CYP3A4
-Target : CHEMBL340
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