Tan Lab | DSigDB

Gene Set: D4 : CTD - Bupropion

Collection

D4 : CTD

Chemical Name

Bupropion ( From PubChem : BUPROPION )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
239.741 g/mol	1	2	3.6902	True

Structure

InChI

InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3/t9-/m0/s1

InChIKey

Links

Gene (17 / 37)

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Source	Type	Gene	Other
CTD	increases(activity)	CASP3	D016642
CTD	increases(cleavage)	CASP3	D016642
CTD	increases(activity)	CASP8	D016642
CTD	increases(activity)	CASP9	D016642
CTD	decreases(reaction)	CYP2B6	D016642
CTD	increases(hydrolysis)	CYP2B6	D016642
CTD	decreases(reaction)	CYP2B6	D016642
CTD	increases(hydroxylation)	CYP2B6	D016642
CTD	affects(metabolic processing)	CYP2B6	D016642
CTD	increases(hydroxylation)	CYP2B6	D016642
CTD	increases(metabolic processing)	CYP2B6	D016642
CTD	increases(chemical synthesis)	CYP2B6	D016642
CTD	increases(metabolic processing)	CYP2B6	D016642
CTD	decreases(reaction)	CYP2B6	D016642
CTD	increases(hydroxylation)	CYP2B6	D016642
CTD	decreases(reaction)	CYP2B6	D016642
CTD	increases(metabolic processing)	CYP2B6	D016642
CTD	increases(phosphorylation)	EIF2S1	D016642
CTD	affects(cotreatment)	FOS	D016642
CTD	increases(expression)	FOS	D016642
CTD	decreases(reaction)	FOS	D016642
CTD	increases(expression)	HMGCS1	D016642
CTD	increases(expression)	HSPA5	D016642
CTD	increases(activity)	MAPK14	D016642
CTD	increases(phosphorylation)	MAPK14	D016642
CTD	increases(activity)	MAPK8	D016642
CTD	increases(phosphorylation)	MAPK8	D016642
CTD	increases(expression)	SCD	D016642
CTD	decreases(reaction)	SLC22A2	D016642
CTD	increases(uptake)	SLC22A2	D016642
CTD	affects(cotreatment)	SLC6A3	D016642
CTD	increases(expression)	SLC6A3	D016642
CTD	decreases(reaction)	SLC6A3	D016642
CTD	affects(response to substance)	SLC6A4	D016642
CTD	increases(expression)	TNFRSF10A	D016642
CTD	increases(expression)	TNFRSF10B	D016642
CTD	decreases(splicing)	XBP1	D016642

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