Tan Lab | DSigDB

Gene Set: D4 : CTD - Iloprost

Collection

D4 : CTD

Chemical Name

Iloprost ( From PubChem : ILOPROST )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
360.487 g/mol	3	4	3.5413	True

Structure

InChI

InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15-,17+,18-,19+,20-,21-/m1/s1

InChIKey

HIFJCPQKFCZDDL-GBSCXWAGSA-N

Links

Gene (14 / 28)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ANGPT1		D016285
CTD	decreases(reaction)			ANGPT1		D016285
CTD	increases(expression)			ANGPT2		D016285
CTD	decreases(reaction)			ANGPT2		D016285
CTD	decreases(reaction)			BMP4		D016285
CTD	increases(expression)			BMP4		D016285
CTD	increases(reaction)			BMP4		D016285
CTD	decreases(expression)			BMPR2		D016285
CTD	decreases(reaction)			BMPR2		D016285
CTD	increases(expression)			FGF2		D016285
CTD	decreases(reaction)			FGF2		D016285
CTD	decreases(expression)			ID1		D016285
CTD	decreases(reaction)			ID1		D016285
CTD	increases(expression)			ID1		D016285
CTD	increases(reaction)			ID1		D016285
CTD	decreases(expression)			IL1B		D016285
CTD	decreases(expression)			IL6		D016285
CTD	decreases(reaction)			MAPK1		D016285
CTD	increases(activity)			MAPK1		D016285
CTD	increases(phosphorylation)			MAPK1		D016285
CTD	decreases(reaction)			MAPK3		D016285
CTD	increases(activity)			MAPK3		D016285
CTD	increases(phosphorylation)			MAPK3		D016285
CTD	affects(binding)			PTGIR		D016285
CTD	decreases(expression)			SELL		D016285
CTD	decreases(reaction)			SMAD6		D016285
CTD	increases(expression)			SMAD6		D016285
PubChem	Potency-Replicate_1	uM	29.849	ESR1	-	GI(Protien) :

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