Tan Lab | DSigDB

Gene Set: D4 : CTD - Didanosine

Collection

D4 : CTD

Chemical Name

Didanosine ( From PubChem : DIDANOSINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
236.227 g/mol	2	6	-0.2105	True

Structure

InChI

InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

InChIKey

Links

Gene (13 / 19)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ALB		D016049
CTD	decreases(expression)			COX2		D016049
CTD	increases(reaction)			COX2		D016049
CTD	affects(cotreatment)			HFE		D016049
CTD	affects(response to substance)			HFE		D016049
CTD	affects(transport)			SLC29A3		D016049
PubChem	Potency	uM	31.623	AR	-	GI(Protien) :
PubChem	None	uM		MBD2	-	GI(Protien) :
PubChem	Potency	uM	7.943	TDP1	-	GI(Protien) :
PubChem	Potency	uM	9.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	11.582	TDP1	-	GI(Protien) :
PubChem	Potency	uM	12.589	TDP1	-	GI(Protien) :
PubChem	None	uM		UHRF1	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340

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