Tan Lab | DSigDB

Gene Set: D4 : CTD - Zalcitabine

Collection

D4 : CTD

Chemical Name

Zalcitabine ( From PubChem : ZALCITABINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
211.218 g/mol	2	6	0.0766	True

Structure

InChI

InChI=1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1

InChIKey

Links

Gene (15 / 23)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ALB		D016047
CTD	increases(response to substance)			APEX1		D016047
CTD	decreases(expression)			COX1		D016047
CTD	decreases(expression)			COX3		D016047
CTD	affects(response to substance)			DCK		D016047
CTD	decreases(expression)			IL2RA		D016047
CTD	increases(reaction)			IL2RA		D016047
CTD	decreases(reaction)			NDUFB11		D016047
CTD	increases(phosphorylation)			NDUFB11		D016047
CTD	affects(transport)			SLC29A3		D016047
CTD	affects(expression)			TFAM		D016047
CTD	decreases(expression)			TK1		D016047
CTD	decreases(expression)			TK2		D016047
CTD	increases(expression)			TYMP		D016047
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	25.119	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	7.499	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	9.200	TDP1	-	GI(Protien) :
PubChem	Potency	uM	10.593	TDP1	-	GI(Protien) :
PubChem	Potency	uM	13.336	TDP1	-	GI(Protien) :
PubChem	Potency	uM	13.336	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	25118.900	MAPK1	-	Target : CHEMBL4040

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