Tan Lab | DSigDB

Gene Set: D4 : CTD - Albendazole

Collection

D4 : CTD

Chemical Name

Albendazole ( From PubChem : ALBENDAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Approved	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
265.331 g/mol	2	5	3.3163	True

Structure

InChI

InChI=1S/C12H15N3O2S/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChIKey

HXHWSAZORRCQMX-UHFFFAOYSA-N

Links

Gene (60 / 124)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(cotreatment)			ADCY7		D015766
CTD	increases(expression)			ADCY7		D015766
CTD	affects(cotreatment)			ARL4C		D015766
CTD	decreases(expression)			ARL4C		D015766
CTD	affects(cotreatment)			BAG3		D015766
CTD	increases(expression)			BAG3		D015766
CTD	increases(expression)			CCL2		D015766
CTD	affects(cotreatment)			CCL3		D015766
CTD	increases(expression)			CCL3		D015766
CTD	affects(cotreatment)			CCR7		D015766
CTD	decreases(expression)			CCR7		D015766
CTD	affects(cotreatment)			CCT3		D015766
CTD	increases(expression)			CCT3		D015766
CTD	affects(cotreatment)			CD86		D015766
CTD	increases(expression)			CD86		D015766
CTD	affects(cotreatment)			CTSL		D015766
CTD	decreases(expression)			CTSL		D015766
CTD	increases(expression)			CXCL8		D015766
CTD	increases(secretion)			CXCL8		D015766
CTD	affects(cotreatment)			CXCL8		D015766
CTD	increases(expression)			CXCL8		D015766
CTD	decreases(reaction)			CXCL8		D015766
CTD	increases(activity)			CYP1A1		D015766
CTD	increases(activity)			CYP1A1		D015766
CTD	increases(expression)			CYP1A1		D015766
CTD	increases(expression)			CYP1A2		D015766
CTD	affects(metabolic processing)			CYP1A2		D015766
CTD	affects(cotreatment)			CYP3A4		D015766
CTD	increases(expression)			CYP3A4		D015766
CTD	affects(cotreatment)			DNAJB1		D015766
CTD	increases(expression)			DNAJB1		D015766
CTD	affects(cotreatment)			DPYSL2		D015766
CTD	increases(expression)			DPYSL2		D015766
CTD	affects(cotreatment)			GEM		D015766
CTD	increases(expression)			GEM		D015766
CTD	affects(cotreatment)			GPR183		D015766
CTD	decreases(expression)			GPR183		D015766
CTD	affects(cotreatment)			HSP90AA1		D015766
CTD	increases(expression)			HSP90AA1		D015766
CTD	affects(cotreatment)			HSP90AB1		D015766
CTD	increases(expression)			HSP90AB1		D015766
CTD	affects(cotreatment)			HSPA4		D015766
CTD	increases(expression)			HSPA4		D015766
CTD	affects(cotreatment)			HSPA8		D015766
CTD	increases(expression)			HSPA8		D015766
CTD	affects(cotreatment)			HSPD1		D015766
CTD	increases(expression)			HSPD1		D015766
CTD	affects(cotreatment)			HSPE1		D015766
CTD	increases(expression)			HSPE1		D015766
CTD	affects(cotreatment)			HSPH1		D015766
CTD	increases(expression)			HSPH1		D015766
CTD	affects(cotreatment)			ICAM1		D015766
CTD	increases(expression)			ICAM1		D015766
CTD	affects(cotreatment)			IL10		D015766
CTD	increases(expression)			IL10		D015766
CTD	affects(cotreatment)			IL1A		D015766
CTD	increases(expression)			IL1A		D015766
CTD	affects(cotreatment)			IL1R1		D015766
CTD	increases(expression)			IL1R1		D015766
CTD	increases(expression)			IL6R		D015766
CTD	affects(cotreatment)			MAP3K8		D015766
CTD	decreases(expression)			MAP3K8		D015766
CTD	decreases(expression)			MAPT		D015766
CTD	affects(cotreatment)			PPID		D015766
CTD	decreases(expression)			PPID		D015766
CTD	affects(cotreatment)			PPIF		D015766
CTD	decreases(expression)			PPIF		D015766
CTD	affects(cotreatment)			PTGES3		D015766
CTD	increases(expression)			PTGES3		D015766
CTD	affects(cotreatment)			SKAP2		D015766
CTD	increases(expression)			SKAP2		D015766
CTD	affects(cotreatment)			SPHK1		D015766
CTD	decreases(expression)			SPHK1		D015766
CTD	affects(cotreatment)			ST13		D015766
CTD	increases(expression)			ST13		D015766
CTD	affects(cotreatment)			TCP1		D015766
CTD	increases(expression)			TCP1		D015766
CTD	affects(cotreatment)			TGIF1		D015766
CTD	decreases(expression)			TGIF1		D015766
CTD	increases(secretion)			TNF		D015766
CTD	decreases(reaction)			TNF		D015766
CTD	affects(cotreatment)			TSC22D1		D015766
CTD	decreases(expression)			TSC22D1		D015766
CTD	increases(expression)			VEGFA		D015766
PubChem	None	uM		ABCB1	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	1.871	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.522	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	14.221	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	34.376	AHR	-	GI(Protien) :
PubChem	None	uM		AHR	-	GI(Protien) :
PubChem	None	uM		APP	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.256	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.275	AR	-	GI(Protien) :
PubChem	Potency	uM	8.877	ATAD5	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.020	ESR1	-	GI(Protien) :
PubChem	Potency	uM	0.453	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.508	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.731	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.820	GMNN	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	16.720	HSPB1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.872	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	21.957	HSPB1	-	GI(Protien) :
PubChem	None	uM		JAK2	-	GI(Protien) :
PubChem	None	uM		KLF5	-	GI(Protien) :
PubChem	None	uM		MCHR1	-	GI(Protien) :
PubChem	None	uM		NPBWR1	-	GI(Protien) :
PubChem	None	uM		NPBWR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.889	NR1H4	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	None	uM		PPARG	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	0.051	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.128	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.316	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.326	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.461	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.891	TDP1	-	GI(Protien) :
PubChem	None	uM		TUBB	-	GI(Protien) :
PubChem	None	uM		VDR	-	GI(Protien) :
ChEMBL	AC50	nM	398.110	CYP1A2	-	Target : CHEMBL3356

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