Tan Lab | DSigDB

Gene Set: D4 : CTD - Bepridil

Collection

D4 : CTD

Chemical Name

Bepridil ( From PubChem : BEPRIDIL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
366.54 g/mol	0	3	4.7681	True

Structure

InChI

InChI=1S/C24H34N2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3/t24-/m1/s1

InChIKey

Links

Gene (14 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			ABCB1		D015764
CTD	increases(transport)			ABCB1		D015764
CTD	increases(expression)			ATF4		D015764
CTD	affects(metabolic processing)			CYP3A4		D015764
CTD	increases(expression)			DDIT3		D015764
CTD	increases(phosphorylation)			EIF2A		D015764
CTD	decreases(activity)			KCNA5		D015764
CTD	affects(binding)			KCNH2		D015764
CTD	decreases(activity)			KCNH2		D015764
CTD	decreases(reaction)			KCNH2		D015764
CTD	increases(transport)			KCNH2		D015764
CTD	decreases(activity)			KCNH2		D015764
CTD	decreases(reaction)			SLC8A1		D015764
CTD	increases(response to substance)			SLC8A1		D015764
CTD	increases(expression)			TNFRSF10B		D015764
CTD	increases(response to substance)			TNFSF10		D015764
PubChem	Potency	uM	10.000	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	2.239	GLS	-	GI(Protien) :
PubChem	Potency	uM	12.589	IDH1	-	GI(Protien) :
PubChem	Potency	uM	5.310	TDP1	-	GI(Protien) :
PubChem	Potency	uM	8.415	TDP1	-	GI(Protien) :
PubChem	Potency	uM	10.000	TDP1	-	GI(Protien) :
PubChem	Potency	uM	12.589	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	10000.000	EHMT2	-	Target : CHEMBL6032

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