Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-Chloroadenosine

Collection

D4 : CTD

Chemical Name

2-Chloroadenosine ( From PubChem : 2-CHLOROADENOSINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
301.686 g/mol	4	9	-0.7454	True

Structure

InChI

InChI=1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1

InChIKey

Links

Gene (16 / 33)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			MTA1		D015762
PubChem	Potency	uM	19.438	AVPR1B	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		EIF2AK3	-	GI(Protien) :
PubChem	Potency	uM	6.310	HIF1A	-	GI(Protien) :
PubChem	Potency	uM	18.356	IDH1	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPK1	-	GI(Protien) :
PubChem	None	uM		NPY1R	-	GI(Protien) :
PubChem	None	uM		NPY2R	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	None	uM		RGS4	-	GI(Protien) :
PubChem	Potency	uM	2.181	RXFP1	-	GI(Protien) :
PubChem	Potency	uM	3.981	RXFP1	-	GI(Protien) :
PubChem	Potency	uM	17.325	RXFP2	-	GI(Protien) :
PubChem	IC50	uM	0.336	SLC5A7	-	GI(Protien) :
PubChem	IC50	uM	0.740	SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	None	uM		SLC5A7	-	GI(Protien) :
PubChem	Potency	uM	1.032	TDP1	-	GI(Protien) :
PubChem	Potency	uM	1.158	TDP1	-	GI(Protien) :
PubChem	Potency	uM	3.663	TDP1	-	GI(Protien) :
PubChem	Potency	uM	4.109	TDP1	-	GI(Protien) :
PubChem	Potency	uM	19.953	TP53	-	GI(Protien) :
ChEMBL	Potency	nM	19438.400	AVPR1B	-	Target : CHEMBL1921
ChEMBL	Potency	nM	6309.600	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	10000.000	MAPK1	-	Target : CHEMBL4040
ChEMBL	Potency	nM	2181.000	RXFP1	-	Target : CHEMBL1293316
ChEMBL	Potency	nM	3981.100	RXFP1	-	Target : CHEMBL1293316
ChEMBL	Potency	nM	17324.500	RXFP2	-	Target : CHEMBL1628482
ChEMBL	Potency	nM	19952.600	TP53	-	Target : CHEMBL4096

Download gene sets