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Gene Set: D4 : CTD - Nocodazole

Collection D4 : CTD
Chemical Name Nocodazole ( From PubChem : NOCODAZOLE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
301.32 g/mol 2 6 3.1067 True
Structure
InChI InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
InChIKey KYRVNWMVYQXFEU-UHFFFAOYSA-N
Links

Gene (58 / 132)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDdecreases(expression)ABCC2
D015739
CTDincreases(expression)ABCC3
D015739
CTDdecreases(activity)AHR
D015739
CTDaffects(binding)ANAPC2
D015739
CTDincreases(reaction)ANAPC2
D015739
CTDdecreases(reaction)AR
D015739
CTDincreases(localization)AR
D015739
CTDdecreases(localization)AR
D015739
CTDaffects(localization)ATP7B
D015739
CTDdecreases(reaction)ATP7B
D015739
CTDincreases(phosphorylation)BCL2
D015739
CTDdecreases(reaction)BCL2
D015739
CTDaffects(reaction)BIRC5
D015739
CTDaffects(response to substance)BIRC5
D015739
CTDdecreases(reaction)BUB1
D015739
CTDincreases(phosphorylation)BUB1
D015739
CTDaffects(cotreatment)BUB1
D015739
CTDincreases(expression)BUB1
D015739
CTDincreases(cleavage)CASP3
D015739
CTDaffects(localization)CCAR1
D015739
CTDdecreases(reaction)CCAR1
D015739
CTDaffects(binding)CCAR1
D015739
CTDincreases(reaction)CCAR1
D015739
CTDincreases(expression)CCAR1
D015739
CTDincreases(expression)CCL2
D015739
CTDincreases(expression)CCNB1
D015739
CTDaffects(cotreatment)CDT1
D015739
CTDdecreases(expression)CDT1
D015739
CTDdecreases(phosphorylation)CDT1
D015739
CTDaffects(localization)CFTR
D015739
CTDdecreases(reaction)CSF2
D015739
CTDincreases(secretion)CSF2
D015739
CTDincreases(expression)CXCL8
D015739
CTDdecreases(reaction)CYP1A1
D015739
CTDincreases(activity)CYP1A1
D015739
CTDincreases(expression)CYP1A1
D015739
CTDdecreases(reaction)EGF
D015739
CTDincreases(expression)EGF
D015739
CTDaffects(cotreatment)FASLG
D015739
CTDdecreases(expression)FASLG
D015739
CTDaffects(cotreatment)FBXO5
D015739
CTDdecreases(expression)FBXO5
D015739
CTDaffects(cotreatment)GMNN
D015739
CTDincreases(ubiquitination)GMNN
D015739
CTDincreases(expression)IL6R
D015739
CTDincreases(phosphorylation)JUN
D015739
CTDaffects(reaction)JUN
D015739
CTDdecreases(reaction)KLK3
D015739
CTDincreases(expression)KLK3
D015739
CTDdecreases(response to substance)LCMT1
D015739
CTDdecreases(reaction)MAPK1
D015739
CTDincreases(activity)MAPK1
D015739
CTDincreases(phosphorylation)MAPK1
D015739
CTDaffects(reaction)MAPK1
D015739
CTDdecreases(reaction)MAPK3
D015739
CTDincreases(activity)MAPK3
D015739
CTDincreases(phosphorylation)MAPK3
D015739
CTDaffects(reaction)MAPK3
D015739
CTDincreases(phosphorylation)MAPK8
D015739
CTDaffects(reaction)MAPK8
D015739
CTDincreases(phosphorylation)MAPK9
D015739
CTDaffects(reaction)MAPK9
D015739
CTDdecreases(expression)MAPT
D015739
CTDincreases(phosphorylation)MYT1
D015739
CTDdecreases(expression)NANOG
D015739
CTDdecreases(reaction)NPC1
D015739
CTDincreases(secretion)NPC1
D015739
CTDaffects(phosphorylation)NPM1
D015739
CTDincreases(cleavage)PARP1
D015739
CTDdecreases(reaction)PARP1
D015739
CTDincreases(cleavage)PARP1
D015739
CTDdecreases(expression)POU5F1
D015739
CTDdecreases(response to substance)PPP2R2A
D015739
CTDdecreases(reaction)QRICH1
D015739
CTDincreases(phosphorylation)QRICH1
D015739
CTDdecreases(reaction)SLC22A2
D015739
CTDincreases(uptake)SLC22A2
D015739
CTDincreases(expression)TP53
D015739
CTDaffects(reaction)TP53
D015739
CTDincreases(phosphorylation)TP53
D015739
CTDaffects(reaction)TYMP
D015739
CTDincreases(activity)TYMP
D015739
CTDincreases(phosphorylation)TYMP
D015739
CTDaffects(cotreatment)TYMP
D015739
CTDdecreases(expression)TYMP
D015739
CTDdecreases(reaction)TYMP
D015739
CTDincreases(cleavage)TYMP
D015739
CTDincreases(expression)VEGFA
D015739
PubChem NoneuMABCB1-GI(Protien) :
PubChem Potency-Replicate_1uM3.758AHR-GI(Protien) :
PubChem AhR Potency (uM)uM5.308AHR-GI(Protien) :
PubChem Ratio Potency (uM)uM0.190AR-GI(Protien) :
PubChem Potency-Replicate_1uM0.213AR-GI(Protien) :
PubChem PotencyuM2.230ATAD5-GI(Protien) :
PubChem PotencyuM2.310ATAD5-GI(Protien) :
PubChem NoneuMCFTR-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem NoneuMCYP1A2-GI(Protien) :
PubChem PotencyuM0.116GMNN-GI(Protien) :
PubChem PotencyuM0.159GMNN-GI(Protien) :
PubChem PotencyuM0.211GMNN-GI(Protien) :
PubChem PotencyuM0.237GMNN-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem NoneuMMDM2-GI(Protien) :
PubChem NoneuMMDM4-GI(Protien) :
PubChem NoneuMMDM4-GI(Protien) :
PubChem Potency-Replicate_1uM0.750NFE2L2-GI(Protien) :
PubChem Ratio Potency (uM)uM1.412NFE2L2-GI(Protien) :
PubChem IC50uM0.833NR0B1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem NoneuMNR0B1-GI(Protien) :
PubChem NoneuMNR1H4-GI(Protien) :
PubChem NoneuMPAX8-GI(Protien) :
PubChem NoneuMPPARG-GI(Protien) :
PubChem NoneuMSTK33-GI(Protien) :
PubChem PotencyuM0.046TDP1-GI(Protien) :
PubChem PotencyuM0.052TDP1-GI(Protien) :
PubChem PotencyuM0.053TDP1-GI(Protien) :
PubChem PotencyuM0.075TDP1-GI(Protien) :
PubChem PotencyuM0.106TDP1-GI(Protien) :
PubChem PotencyuM0.130TDP1-GI(Protien) :
PubChem PotencyuM0.141TDP1-GI(Protien) :
PubChem PotencyuM0.178TDP1-GI(Protien) :
PubChem NoneuMVDR-GI(Protien) :
ChEMBLPotencynM2310.000ATAD5
-Target : CHEMBL1741209
ChEMBLPotencynM794.300CREBBP
-Target : CHEMBL5747
ChEMBLAC50nM1584.890CYP1A2
-Target : CHEMBL3356
ChEMBLAC50nM794.330CYP1A2
-Target : CHEMBL3356
ChEMBLPotencynM115.800GMNN
-Target : CHEMBL1293278
ChEMBLPotencynM158.500GMNN
-Target : CHEMBL1293278
ChEMBLActivity-HSPB1
-Target : CHEMBL5976
ChEMBLActivity-HSPB1
-Target : CHEMBL5976
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Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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