Tan Lab | DSigDB

Gene Set: D4 : CTD - Fluconazole

Collection

D4 : CTD

Chemical Name

Fluconazole ( From PubChem : FLUCONAZOLE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Approved	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
306.271 g/mol	1	7	0.7358	True

Structure

InChI

InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2

InChIKey

Links

Gene (8 / 20)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			CYP2C19		D015725
CTD	increases(metabolic processing)			CYP2C19		D015725
CTD	decreases(activity)			CYP2C19		D015725
CTD	affects(metabolic processing)			CYP2C9		D015725
CTD	affects(reaction)			CYP2C9		D015725
CTD	affects(metabolic processing)			CYP2C9		D015725
CTD	decreases(reaction)			CYP2C9		D015725
CTD	decreases(activity)			CYP2C9		D015725
CTD	decreases(activity)			CYP3A4		D015725
CTD	decreases(activity)			CYP51A1		D015725
CTD	affects(cotreatment)			UGT2B7		D015725
CTD	decreases(reaction)			UGT2B7		D015725
CTD	increases(glucuronidation)			UGT2B7		D015725
PubChem	AC50_uM	uM	4.687	HSP90AA1	-	GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340

Download gene sets