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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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Collection	D4 : CTD
Chemical Name	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ( From PubChem : MPTP )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 173.254 g/mol 0 1 2.3434 True
Structure
InChI	InChI=1S/C12H15N/c1-13-9-7-12(8-10-13)11-5-3-2-4-6-11/h2-7H,8-10H2,1H3
InChIKey	PLRACCBDVIHHLZ-UHFFFAOYSA-N
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Gene (9 / 18) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(metabolic processing) CYP2D6 D015632 CTD affects(cotreatment) GDNF D015632 CTD decreases(response to substance) GDNF D015632 CTD decreases(reaction) GPX1 D015632 CTD increases(expression) GPX1 D015632 CTD decreases(reaction) MAOB D015632 CTD increases(oxidation) MAOB D015632 CTD decreases(phosphorylation) MAPK1 D015632 CTD increases(reaction) MAPK1 D015632 CTD decreases(phosphorylation) MAPK3 D015632 CTD increases(reaction) MAPK3 D015632 CTD affects(localization) SNCA D015632 CTD increases(expression) SNCA D015632 CTD decreases(reaction) SNCA D015632 CTD increases(reaction) SNCA D015632 CTD decreases(response to substance) XBP1 D015632 ChEMBL Inhibition - MAOA - Target : CHEMBL1951 ChEMBL Inhibition - MAOA - Target : CHEMBL1951
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