Tan Lab | DSigDB

Gene Set: D4 : CTD - Roxithromycin

Collection

D4 : CTD

Chemical Name

Roxithromycin ( From PubChem : ROXITHROMYCIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
837.047 g/mol	5	17	2.2096	False(2/4)

Structure

InChI

InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3

InChIKey

RXZBMPWDPOLZGW-UHFFFAOYSA-N

Links

Gene (13 / 23)

⊖ Less

Source	Type	Unit	Gene	PMID	Other
CTD	decreases(expression)		BCL2		D015575
CTD	decreases(reaction)		CXCL8		D015575
CTD	increases(expression)		CXCL8		D015575
CTD	decreases(activity)		CYP2B6		D015575
CTD	decreases(reaction)		CYP3A4		D015575
CTD	increases(hydroxylation)		CYP3A4		D015575
CTD	decreases(activity)		CYP3A4		D015575
CTD	decreases(expression)		CYP3A4		D015575
CTD	increases(expression)		FASLG		D015575
CTD	decreases(reaction)		IL1B		D015575
CTD	increases(expression)		IL1B		D015575
CTD	decreases(reaction)		IL6		D015575
CTD	increases(expression)		IL6		D015575
CTD	decreases(expression)		ITGB4		D015575
CTD	decreases(expression)		LAMC2		D015575
CTD	decreases(reaction)		NOS2		D015575
CTD	increases(expression)		NOS2		D015575
CTD	decreases(reaction)		TNF		D015575
CTD	increases(expression)		TNF		D015575
PubChem	None	uM	ABCB1	-	GI(Protien) :
ChEMBL	Inhibition	-	F2RL1	-	Target : CHEMBL5963
ChEMBL	Inhibition	-	F2RL1	-	Target : CHEMBL5963
ChEMBL	Inhibition	-	F2RL1	-	Target : CHEMBL5963

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