Tan Lab | DSigDB

Gene Set: D4 : CTD - Nimustine

Collection

D4 : CTD

Chemical Name

Nimustine ( From PubChem : NIMUSTINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
272.692 g/mol	2	8	1.7711	True

Structure

InChI

InChI=1S/C9H13ClN6O2/c1-6-12-4-7(8(11)14-6)5-13-9(17)16(15-18)3-2-10/h4H,2-3,5H2,1H3,(H,13,17)(H2,11,12,14)

InChIKey

VFEDRRNHLBGPNN-UHFFFAOYSA-N

Links

Gene (14 / 41)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCC1		D015376
CTD	increases(transport)			ABCC1		D015376
CTD	affects(reaction)			CHEK1		D015376
CTD	increases(phosphorylation)			CHEK1		D015376
CTD	affects(reaction)			DDB2		D015376
CTD	increases(expression)			DDB2		D015376
CTD	decreases(reaction)			FOS		D015376
CTD	increases(expression)			FOS		D015376
CTD	affects(reaction)			FOSL1		D015376
CTD	increases(phosphorylation)			FOSL1		D015376
CTD	affects(response to substance)			FOSL1		D015376
CTD	increases(expression)			FOSL1		D015376
CTD	increases(expression)			FXN		D015376
CTD	increases(expression)			GCLC		D015376
CTD	decreases(reaction)			JUN		D015376
CTD	increases(expression)			JUN		D015376
CTD	affects(binding)			JUN		D015376
CTD	increases(reaction)			JUN		D015376
CTD	increases(phosphorylation)			JUN		D015376
CTD	decreases(response to substance)			MGMT		D015376
CTD	increases(reaction)			MGMT		D015376
CTD	decreases(response to substance)			MGMT		D015376
CTD	affects(cotreatment)			MGMT		D015376
CTD	increases(expression)			MGMT		D015376
CTD	decreases(activity)			MGMT		D015376
CTD	increases(response to substance)			MGMT		D015376
CTD	affects(response to substance)			TAP1		D015376
CTD	affects(reaction)			TP53		D015376
CTD	increases(expression)			TP53		D015376
CTD	affects(response to substance)			TP53		D015376
CTD	decreases(reaction)			TREX1		D015376
CTD	increases(expression)			TREX1		D015376
CTD	affects(binding)			TREX1		D015376
CTD	increases(reaction)			TREX1		D015376
CTD	affects(response to substance)			TREX1		D015376
CTD	increases(expression)			XPC		D015376
CTD	affects(reaction)			XPC		D015376
PubChem	Potency	uM	16.834	EHMT2	-	GI(Protien) :
PubChem	Potency	uM	50.119	EHMT2	-	GI(Protien) :
ChEMBL	Potency	nM	16833.600	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	50118.700	EHMT2	-	Target : CHEMBL6032

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