Tan Lab | DSigDB

Gene Set: D4 : CTD - Oxyquinoline

Collection

D4 : CTD

Chemical Name

Oxyquinoline ( From PubChem : 8-HYDROXYQUINOLINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
145.158 g/mol	1	2	1.9404	True

Structure

InChI

InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChIKey

MCJGNVYPOGVAJF-UHFFFAOYSA-N

Links

Gene (239 / 258)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ABCG5		D015125
CTD	decreases(expression)			ACAD11		D015125
CTD	decreases(expression)			ACAT2		D015125
CTD	decreases(expression)			ACSL3		D015125
CTD	decreases(expression)			ACY1		D015125
CTD	decreases(expression)			ADH4		D015125
CTD	decreases(expression)			ADM		D015125
CTD	decreases(expression)			ADSSL1		D015125
CTD	decreases(expression)			AGA		D015125
CTD	increases(expression)			AKR1B10		D015125
CTD	increases(expression)			AKR1C1		D015125
CTD	increases(expression)			AKR1C2		D015125
CTD	increases(expression)			ALDH1L1		D015125
CTD	decreases(expression)			AMDHD1		D015125
CTD	increases(expression)			AMOT		D015125
CTD	increases(expression)			ANKRD1		D015125
CTD	decreases(expression)			ANKRD32		D015125
CTD	decreases(expression)			ANKRD37		D015125
CTD	decreases(expression)			APBB2		D015125
CTD	decreases(expression)			APITD1		D015125
CTD	decreases(expression)			AQP3		D015125
CTD	increases(expression)			ARG1		D015125
CTD	increases(expression)			ARG2		D015125
CTD	decreases(expression)			ARHGAP44		D015125
CTD	decreases(expression)			ARRDC3		D015125
CTD	decreases(expression)			ATP6V0A2		D015125
CTD	increases(expression)			AZGP1		D015125
CTD	decreases(expression)			BHLHE40		D015125
CTD	decreases(expression)			BMP2K		D015125
CTD	increases(expression)			BPIFB2		D015125
CTD	increases(expression)			C10ORF10		D015125
CTD	decreases(expression)			C12ORF4		D015125
CTD	decreases(expression)			C19ORF80		D015125
CTD	increases(expression)			C3ORF35		D015125
CTD	decreases(expression)			C4ORF32		D015125
CTD	decreases(expression)			C9ORF41		D015125
CTD	increases(expression)			CCBL1		D015125
CTD	decreases(expression)			CCDC18		D015125
CTD	decreases(expression)			CCNE2		D015125
CTD	decreases(expression)			CDC6		D015125
CTD	decreases(expression)			CDC7		D015125
CTD	decreases(expression)			CDC73		D015125
CTD	decreases(expression)			CDH1		D015125
CTD	increases(expression)			CDKN1A		D015125
CTD	decreases(expression)			CDO1		D015125
CTD	decreases(expression)			CENPK		D015125
CTD	decreases(expression)			CHAC2		D015125
CTD	increases(expression)			CHST15		D015125
CTD	decreases(expression)			CLGN		D015125
CTD	decreases(expression)			CLHC1		D015125
CTD	decreases(expression)			CMTR2		D015125
CTD	decreases(expression)			CPA6		D015125
CTD	increases(expression)			CREBRF		D015125
CTD	decreases(expression)			CSAD		D015125
CTD	decreases(expression)			CSTA		D015125
CTD	decreases(expression)			CXORF57		D015125
CTD	increases(expression)			CYGB		D015125
CTD	decreases(expression)			CYP24A1		D015125
CTD	decreases(expression)			CYP51A1		D015125
CTD	increases(expression)			CYR61		D015125
CTD	decreases(expression)			DDIT4		D015125
CTD	decreases(expression)			DHFRL1		D015125
CTD	decreases(expression)			DMXL1		D015125
CTD	decreases(expression)			DNAJB9		D015125
CTD	decreases(expression)			DNAJC3		D015125
CTD	increases(expression)			DRAM1		D015125
CTD	increases(expression)			DSE		D015125
CTD	decreases(expression)			E2F8		D015125
CTD	decreases(expression)			EED		D015125
CTD	decreases(expression)			EFCAB7		D015125
CTD	affects(binding)			EGFR		D015125
CTD	increases(phosphorylation)			EGFR		D015125
CTD	increases(expression)			EMP3		D015125
CTD	decreases(expression)			EOGT		D015125
CTD	increases(expression)			EPS8L3		D015125
CTD	decreases(expression)			ESM1		D015125
CTD	decreases(expression)			ETNPPL		D015125
CTD	increases(expression)			ETV4		D015125
CTD	decreases(expression)			FAM13A		D015125
CTD	decreases(expression)			FAM13C		D015125
CTD	decreases(expression)			FAM73A		D015125
CTD	decreases(expression)			FDPS		D015125
CTD	increases(expression)			FILIP1L		D015125
CTD	increases(expression)			FNIP2		D015125
CTD	decreases(expression)			FOS		D015125
CTD	decreases(expression)			FRK		D015125
CTD	increases(expression)			FRY		D015125
CTD	increases(expression)			FXYD1		D015125
CTD	increases(expression)			G6PC		D015125
CTD	decreases(expression)			GATA6		D015125
CTD	increases(expression)			GBP2		D015125
CTD	increases(expression)			GCKR		D015125
CTD	decreases(expression)			GDAP1		D015125
CTD	decreases(expression)			GINS4		D015125
CTD	decreases(expression)			GOLGA8A		D015125
CTD	decreases(expression)			GPX8		D015125
CTD	increases(expression)			GRB7		D015125
CTD	decreases(expression)			GUF1		D015125
CTD	decreases(expression)			HAL		D015125
CTD	decreases(expression)			HAMP		D015125
CTD	decreases(expression)			HAUS3		D015125
CTD	decreases(expression)			HEATR3		D015125
CTD	decreases(expression)			HECTD2		D015125
CTD	decreases(expression)			HEY1		D015125
CTD	decreases(expression)			HILPDA		D015125
CTD	decreases(expression)			HIRA		D015125
CTD	decreases(expression)			HIST1H2BG		D015125
CTD	increases(expression)			HIVEP2		D015125
CTD	decreases(expression)			HMGCR		D015125
CTD	decreases(expression)			HMOX1		D015125
CTD	affects(localization)			HSPA1A		D015125
CTD	increases(expression)			HSPA1A		D015125
CTD	affects(localization)			HSPA8		D015125
CTD	decreases(expression)			ID3		D015125
CTD	increases(expression)			IGFBP1		D015125
CTD	decreases(expression)			IGFBP3		D015125
CTD	decreases(expression)			IL6ST		D015125
CTD	decreases(expression)			INHBE		D015125
CTD	decreases(expression)			INTU		D015125
CTD	decreases(expression)			IRAK1BP1		D015125
CTD	increases(expression)			ISX		D015125
CTD	decreases(expression)			KBTBD8		D015125
CTD	decreases(expression)			KCTD18		D015125
CTD	decreases(expression)			KIAA0754		D015125
CTD	increases(expression)			LCN15		D015125
CTD	decreases(expression)			LEAP2		D015125
CTD	decreases(expression)			LGALS3		D015125
CTD	decreases(expression)			LINC00597		D015125
CTD	decreases(expression)			LIPG		D015125
CTD	decreases(expression)			LOX		D015125
CTD	increases(expression)			LPPR1		D015125
CTD	increases(expression)			LRRC75A-AS1		D015125
CTD	decreases(expression)			MALAT1		D015125
CTD	decreases(expression)			MANF		D015125
CTD	decreases(expression)			MASTL		D015125
CTD	decreases(expression)			MFSD8		D015125
CTD	decreases(expression)			MIXL1		D015125
CTD	decreases(expression)			MSMO1		D015125
CTD	decreases(expression)			MT1F		D015125
CTD	decreases(expression)			MT1G		D015125
CTD	decreases(expression)			NAP1L5		D015125
CTD	increases(expression)			NDRG1		D015125
CTD	decreases(expression)			NEIL3		D015125
CTD	increases(expression)			NUPR1		D015125
CTD	decreases(expression)			OLFML3		D015125
CTD	increases(expression)			OSGIN1		D015125
CTD	decreases(expression)			PABPC1L		D015125
CTD	affects(binding)			PABPN1		D015125
CTD	decreases(reaction)			PABPN1		D015125
CTD	increases(expression)			PALLD		D015125
CTD	decreases(expression)			PAQR3		D015125
CTD	decreases(expression)			PCK1		D015125
CTD	decreases(expression)			PCOLCE2		D015125
CTD	decreases(expression)			PDGFRL		D015125
CTD	decreases(expression)			PDK1		D015125
CTD	decreases(expression)			PDP2		D015125
CTD	decreases(expression)			PFKFB3		D015125
CTD	increases(expression)			PGC		D015125
CTD	decreases(expression)			PIGW		D015125
CTD	decreases(expression)			PLAC8		D015125
CTD	decreases(expression)			PLIN2		D015125
CTD	increases(expression)			PLK2		D015125
CTD	decreases(expression)			PLP1		D015125
CTD	increases(expression)			PPP1R16A		D015125
CTD	decreases(expression)			PPP1R3C		D015125
CTD	decreases(expression)			PPP3R1		D015125
CTD	decreases(expression)			PRORSD1P		D015125
CTD	decreases(expression)			PTCD2		D015125
CTD	increases(expression)			PTCHD4		D015125
CTD	increases(expression)			PTMS		D015125
CTD	decreases(expression)			QPCT		D015125
CTD	decreases(expression)			RABGAP1L		D015125
CTD	increases(expression)			RBM24		D015125
CTD	decreases(expression)			REEP3		D015125
CTD	increases(expression)			RGCC		D015125
CTD	decreases(expression)			RNFT1		D015125
CTD	decreases(expression)			RPGRIP1L		D015125
CTD	increases(expression)			RSL1D1		D015125
CTD	decreases(expression)			SDF2L1		D015125
CTD	decreases(expression)			SENP5		D015125
CTD	increases(expression)			SERPINA7		D015125
CTD	decreases(expression)			SERPINE1		D015125
CTD	decreases(expression)			SGK2		D015125
CTD	decreases(expression)			SLC16A6		D015125
CTD	decreases(expression)			SLC22A3		D015125
CTD	decreases(expression)			SLC30A1		D015125
CTD	decreases(expression)			SLC30A10		D015125
CTD	decreases(expression)			SLC35B3		D015125
CTD	decreases(expression)			SLC35D1		D015125
CTD	decreases(expression)			SLC51A		D015125
CTD	increases(expression)			SLCO4A1		D015125
CTD	decreases(expression)			SMIM13		D015125
CTD	increases(expression)			SORBS3		D015125
CTD	decreases(expression)			SPA17		D015125
CTD	decreases(expression)			SPAG4		D015125
CTD	decreases(expression)			SPC25		D015125
CTD	decreases(expression)			SPIN4		D015125
CTD	increases(expression)			SPON2		D015125
CTD	decreases(expression)			SRD5A3		D015125
CTD	increases(expression)			SRXN1		D015125
CTD	increases(expression)			SSUH2		D015125
CTD	decreases(expression)			STIL		D015125
CTD	increases(expression)			STOM		D015125
CTD	increases(expression)			SULT2A1		D015125
CTD	decreases(expression)			TEX9		D015125
CTD	increases(expression)			THAP2		D015125
CTD	decreases(expression)			TIMM8A		D015125
CTD	decreases(expression)			TM7SF2		D015125
CTD	increases(expression)			TMCC1		D015125
CTD	decreases(expression)			TMEM116		D015125
CTD	decreases(expression)			TMEM128		D015125
CTD	increases(expression)			TNFAIP3		D015125
CTD	increases(expression)			TNFSF10		D015125
CTD	decreases(expression)			TTC30B		D015125
CTD	increases(expression)			TTR		D015125
CTD	increases(expression)			TTYH3		D015125
CTD	decreases(expression)			TUBA1A		D015125
CTD	affects(expression)			TUBB1		D015125
CTD	decreases(expression)			TUBE1		D015125
CTD	increases(expression)			TXNIP		D015125
CTD	increases(expression)			TYMSOS		D015125
CTD	increases(expression)			UBD		D015125
CTD	increases(metabolic processing)			UGT2B15		D015125
CTD	decreases(expression)			USP43		D015125
CTD	increases(expression)			UTRN		D015125
CTD	increases(expression)			YPEL3		D015125
CTD	increases(expression)			ZBTB38		D015125
CTD	decreases(expression)			ZBTB8A		D015125
CTD	decreases(expression)			ZFP69B		D015125
CTD	decreases(expression)			ZWINT		D015125
PubChem	Potency-Replicate_1	uM	2.169	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	2.744	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.216	AR	-	GI(Protien) :
PubChem	Potency	uM	10.000	BAZ2B	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.545	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.974	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	18.834	CYP19A1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.208	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.309	HSPB1	-	GI(Protien) :
PubChem	None	uM		KCNK9	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	6.144	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.738	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	37.578	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	42.163	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	63.827	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	66.824	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	11.100	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	15.206	NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		NR3C1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		PPARG	-	GI(Protien) :
PubChem	Potency	uM	3.548	SMAD3	-	GI(Protien) :
PubChem	None	uM		STK33	-	GI(Protien) :
PubChem	Potency	uM	4.732	TDP1	-	GI(Protien) :
PubChem	Potency	uM	5.309	TDP1	-	GI(Protien) :
PubChem	Potency	uM	6.859	TDP1	-	GI(Protien) :
PubChem	Potency	uM	9.688	TDP1	-	GI(Protien) :
PubChem	None	uM		VDR	-	GI(Protien) :
ChEMBL	Potency	nM	10000.000	BAZ2B	-	Target : CHEMBL1741220

Download gene sets

gmt, text, Detailed text