DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : CTD - 5,8,11,14-Eicosatetraynoic Acid

---

Collection	D4 : CTD
Chemical Name	5,8,11,14-Eicosatetraynoic Acid ( From PubChem : ETYA )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 296.403 g/mol 1 2 4.0055 True
Structure
InChI	InChI=1S/C20H24O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h2-5,8,11,14,17-19H2,1H3,(H,21,22)
InChIKey	MGLDCXPLYOWQRP-UHFFFAOYSA-N
Links
Gene (24 / 43) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(expression) CES1 D015117 CTD affects(binding) PPARA D015117 CTD increases(activity) PPARA D015117 PubChem None uM ADRBK1 - GI(Protien) : PubChem None uM ADRBK1 - GI(Protien) : PubChem None uM APAF1 - GI(Protien) : PubChem Average IC50 uM 0.860 APOBEC3G - GI(Protien) : PubChem Potency uM 3.981 BAZ2B - GI(Protien) : PubChem Potency uM 12.589 BLM - GI(Protien) : PubChem None uM DUSP1 - GI(Protien) : PubChem None uM DUSP1 - GI(Protien) : PubChem None uM DUSP1 - GI(Protien) : PubChem None uM DUSP1 - GI(Protien) : PubChem IC50 uM DUSP3 - GI(Protien) : PubChem Potency uM 10.000 EHMT2 - GI(Protien) : PubChem None uM EIF4G1 - GI(Protien) : PubChem IC50 uM EIF4H - GI(Protien) : PubChem Potency uM 2.239 KAT2A - GI(Protien) : PubChem IC50 uM 0.441 MCL1 - GI(Protien) : PubChem Absolute IC50 uM 1.780 MCL1 - GI(Protien) : PubChem None uM MCL1 - GI(Protien) : PubChem None uM MCL1 - GI(Protien) : PubChem None uM MCL1 - GI(Protien) : PubChem None uM MCL1 - GI(Protien) : PubChem IC50 uM PHOSPHO1 - GI(Protien) : PubChem None uM PLA2G7 - GI(Protien) : PubChem Potency uM 1.122 POLB - GI(Protien) : PubChem Potency uM 10.000 POLK - GI(Protien) : PubChem IC50 uM 15.400 PTPN7 - GI(Protien) : PubChem IC50_Mean uM 20.000 PTPN7 - GI(Protien) : PubChem IC50 uM SAE1 - GI(Protien) : PubChem IC50 uM UBA2 - GI(Protien) : PubChem IC50 uM UBE2I - GI(Protien) : ChEMBL Potency nM 3981.100 BAZ2B - Target : CHEMBL1741220 ChEMBL Potency nM 12589.300 BLM - Target : CHEMBL1293237 ChEMBL Potency nM 10000.000 EHMT2 - Target : CHEMBL6032 ChEMBL Potency nM 2238.700 KAT2A - Target : CHEMBL5501 ChEMBL Potency nM 15848.900 KDM4E - Target : CHEMBL1293226 ChEMBL IC50 nM 441.490 MCL1 - Target : CHEMBL4361 ChEMBL Potency nM 1122.000 POLB - Target : CHEMBL2392 ChEMBL IC50 nM 15400.000 PTPN7 - Target : CHEMBL2219 ChEMBL Potency nM 28183.800 RECQL - Target : CHEMBL1293236 ChEMBL Potency nM 1122.000 RECQL - Target : CHEMBL1293236
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).