Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-Naphthylamine

Collection

D4 : CTD

Chemical Name

2-Naphthylamine ( From PubChem : 2-NAPHTHALENAMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
143.185 g/mol	1	1	3.0032	True

Structure

InChI

InChI=1S/C10H9N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H,11H2

InChIKey

JBIJLHTVPXGSAM-UHFFFAOYSA-N

Links

Gene (96 / 100)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			AATK		D015081
CTD	decreases(expression)			AMHR2		D015081
CTD	decreases(expression)			BAD		D015081
CTD	increases(expression)			BCL2A1		D015081
CTD	decreases(expression)			BRCA1		D015081
CTD	decreases(expression)			BTF3		D015081
CTD	increases(expression)			BTK		D015081
CTD	decreases(expression)			C5AR1		D015081
CTD	increases(expression)			CARTPT		D015081
CTD	increases(expression)			CBL		D015081
CTD	decreases(expression)			CCL16		D015081
CTD	increases(expression)			CCL5		D015081
CTD	increases(expression)			CCR5		D015081
CTD	decreases(expression)			CCR6		D015081
CTD	increases(expression)			CD4		D015081
CTD	increases(expression)			CD59		D015081
CTD	decreases(expression)			CKS1B		D015081
CTD	decreases(expression)			CREB1		D015081
CTD	decreases(expression)			CXCL2		D015081
CTD	decreases(expression)			CXCR2		D015081
CTD	increases(activity)			CYP1A2		D015081
CTD	increases(reduction)			CYP2S1		D015081
CTD	increases(expression)			DEDD		D015081
CTD	decreases(expression)			DFFB		D015081
CTD	decreases(expression)			DNASE2		D015081
CTD	decreases(expression)			EDNRA		D015081
CTD	increases(metabolic processing)			ENPEP		D015081
CTD	decreases(expression)			EPHA3		D015081
CTD	increases(expression)			EPHB3		D015081
CTD	increases(expression)			EPO		D015081
CTD	increases(expression)			EZR		D015081
CTD	decreases(expression)			FASLG		D015081
CTD	decreases(expression)			FLT3		D015081
CTD	decreases(expression)			FN1		D015081
CTD	increases(expression)			FSCN1		D015081
CTD	increases(expression)			GDF1		D015081
CTD	decreases(expression)			HLTF		D015081
CTD	decreases(expression)			IFI6		D015081
CTD	decreases(expression)			IFNAR1		D015081
CTD	decreases(expression)			IGHM		D015081
CTD	decreases(expression)			IL10		D015081
CTD	decreases(expression)			IL3RA		D015081
CTD	decreases(expression)			IL9		D015081
CTD	decreases(expression)			ITGAL		D015081
CTD	increases(expression)			KLF11		D015081
CTD	increases(metabolic processing)			LNPEP		D015081
CTD	decreases(expression)			LTB		D015081
CTD	increases(expression)			MADD		D015081
CTD	affects(metabolic processing)			MPO		D015081
CTD	decreases(expression)			MST1		D015081
CTD	increases(activity)			NAT1		D015081
CTD	increases(activity)			NAT2		D015081
CTD	decreases(expression)			NFKBIE		D015081
CTD	decreases(expression)			NFYB		D015081
CTD	decreases(expression)			NME3		D015081
CTD	increases(expression)			NOS2		D015081
CTD	affects(binding)			NPY5R		D015081
CTD	decreases(activity)			NPY5R		D015081
CTD	decreases(expression)			OPRK1		D015081
CTD	decreases(expression)			PLD1		D015081
CTD	increases(expression)			PLD2		D015081
CTD	decreases(expression)			POU2AF1		D015081
CTD	increases(expression)			POU2F1		D015081
CTD	increases(expression)			PRKAR2B		D015081
CTD	decreases(expression)			PSMB6		D015081
CTD	decreases(expression)			PTAFR		D015081
CTD	decreases(expression)			PTX3		D015081
CTD	decreases(expression)			RARG		D015081
CTD	increases(expression)			RGS1		D015081
CTD	increases(metabolic processing)			RNPEP		D015081
CTD	decreases(expression)			RPL7A		D015081
CTD	increases(expression)			RPS25		D015081
CTD	decreases(expression)			RUNX1T1		D015081
CTD	increases(expression)			S100A10		D015081
CTD	decreases(expression)			SLC9A3R2		D015081
CTD	increases(expression)			SMAD9		D015081
CTD	increases(expression)			SNCA		D015081
CTD	decreases(expression)			SREBF1		D015081
CTD	decreases(expression)			STAT2		D015081
CTD	increases(expression)			STK25		D015081
CTD	increases(sulfation)			SULT1A1		D015081
CTD	increases(sulfation)			SULT1A2		D015081
CTD	increases(sulfation)			SULT1A3		D015081
CTD	increases(sulfation)			SULT1C2		D015081
CTD	increases(metabolic processing)			SULT4A1		D015081
CTD	increases(expression)			SUPT4H1		D015081
CTD	decreases(expression)			TFDP1		D015081
CTD	decreases(expression)			TNFRSF1A		D015081
CTD	decreases(expression)			TP53		D015081
CTD	increases(expression)			TSHR		D015081
CTD	increases(expression)			UBE2I		D015081
CTD	increases(expression)			UGP2		D015081
CTD	decreases(expression)			UQCRFS1		D015081
CTD	decreases(expression)			VIM		D015081
CTD	increases(expression)			ZFYVE9		D015081
PubChem	AhR Potency (uM)	uM	18.665	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	20.942	AHR	-	GI(Protien) :
PubChem	AhR Potency (uM)	uM	24.337	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.306	AHR	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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