Tan Lab | DSigDB

Gene Set: D4 : CTD - 2-Acetylaminofluorene

Collection

D4 : CTD

Chemical Name

2-Acetylaminofluorene ( From PubChem : 2-ACETAMIDOFLUORENE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
223.27 g/mol	1	2	3.2892	True

Structure

InChI

InChI=1S/C15H13NO/c1-10(17)16-13-6-7-15-12(9-13)8-11-4-2-3-5-14(11)15/h2-7,9H,8H2,1H3,(H,16,17)

InChIKey

CZIHNRWJTSTCEX-UHFFFAOYSA-N

Links

Gene (24 / 41)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			ABCB1		D015073
CTD	increases(activity)			ABCB1		D015073
CTD	increases(expression)			ABCB1		D015073
CTD	affects(binding)			ABCB1		D015073
CTD	affects(reaction)			ABCB1		D015073
CTD	increases(expression)			ABCC10		D015073
CTD	increases(expression)			ABCC2		D015073
CTD	increases(expression)			ABCC2		D015073
CTD	increases(expression)			ABCC3		D015073
CTD	increases(activity)			AKT1		D015073
CTD	increases(expression)			AKT1		D015073
CTD	increases(phosphorylation)			AKT1		D015073
CTD	increases(hydrolysis)			CYP1A1		D015073
CTD	affects(metabolic processing)			CYP1A2		D015073
CTD	increases(activity)			CYP1A2		D015073
CTD	increases(hydrolysis)			CYP1A2		D015073
CTD	increases(expression)			GCLC		D015073
CTD	increases(expression)			ID1		D015073
CTD	increases(activity)			IKBKB		D015073
CTD	increases(activity)			NAT1		D015073
CTD	increases(activity)			NAT2		D015073
CTD	affects(binding)			NFKB1		D015073
CTD	affects(reaction)			NFKB1		D015073
CTD	increases(expression)			NFKB1		D015073
CTD	increases(expression)			NR1I2		D015073
CTD	increases(activity)			RAC1		D015073
CTD	increases(expression)			RAC1		D015073
CTD	increases(activity)			RELA		D015073
CTD	affects(binding)			RELA		D015073
CTD	affects(reaction)			RELA		D015073
CTD	increases(expression)			RELA		D015073
CTD	increases(expression)			RRM2B		D015073
CTD	increases(expression)			TP53		D015073
CTD	increases(glucuronidation)			UGT1A9		D015073
PubChem	AhR Potency (uM)	uM	34.901	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	55.315	AHR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	44.342	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	11.037	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	27.723	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	27.723	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :

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