Tan Lab | DSigDB

Gene Set: D4 : CTD - Ziram

Collection

D4 : CTD

Chemical Name

Ziram ( From PubChem : ZIRAM )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
305.813 g/mol	0	6	0.7571	True

Structure

InChI

InChI=1S/2C3H7NS2.Zn/c2*1-4(2)3(5)6;/h2*1-2H3,(H,5,6);/q;;+2/p-2

InChIKey

DUBNHZYBDBBJHD-UHFFFAOYSA-L

Links

Gene (29 / 43)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(activity)			CASP3		D015039
CTD	increases(activity)			CASP8		D015039
CTD	increases(activity)			CASP9		D015039
CTD	affects(localization)			CYCS		D015039
CTD	decreases(expression)			FCGR3A		D015039
CTD	decreases(expression)			GNLY		D015039
CTD	decreases(expression)			GZMA		D015039
CTD	decreases(expression)			GZMB		D015039
CTD	decreases(expression)			GZMK		D015039
CTD	increases(activity)			MAPK1		D015039
CTD	increases(activity)			MAPK3		D015039
CTD	decreases(expression)			PRF1		D015039
CTD	decreases(reaction)			TNF		D015039
CTD	increases(secretion)			TNF		D015039
CTD	decreases(activity)			TPO		D015039
CTD	decreases(activity)			UBA1		D015039
PubChem	Potency	uM	2.818	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	3.162	ALOX15	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.684	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	0.967	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	33.492	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM		AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.060	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.243	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	4.357	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.562	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	23.891	ESR1	-	GI(Protien) :
PubChem	Potency	uM	28.184	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	30.828	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.024	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.382	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	22.387	KCNH2		GI(Protien) :
PubChem	Potency	uM	22.387	KCNH2		GI(Protien) :
PubChem	Potency	uM	31.623	MAPK1	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	31.623	NR1I2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.338	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	43.572	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	11.727	PPARG	-	GI(Protien) :
PubChem	Potency	uM	8.912	THRB	-	GI(Protien) :
PubChem	Potency	uM	15.849	TP53	-	GI(Protien) :
PubChem	Potency	uM	10.000	VDR	-	GI(Protien) :

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