Tan Lab | DSigDB

Gene Set: D4 : CTD - Zeranol

Collection

D4 : CTD

Chemical Name

Zeranol ( From PubChem : ZERANOL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
322.396 g/mol	3	5	3.2908	True

Structure

InChI

InChI=1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m1/s1

InChIKey

DWTTZBARDOXEAM-OCCSQVGLSA-N

Links

Gene (34 / 63)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(reaction)			BAX		D015029
CTD	increases(expression)			BAX		D015029
CTD	decreases(expression)			BCL2		D015029
CTD	decreases(reaction)			BCL2		D015029
CTD	increases(expression)			CCND1		D015029
CTD	increases(expression)			CITED2		D015029
CTD	decreases(reaction)			CRH		D015029
CTD	increases(expression)			CRH		D015029
CTD	affects(expression)			EDN1		D015029
CTD	decreases(reaction)			EDN1		D015029
CTD	affects(binding)			ESR1		D015029
CTD	increases(activity)			ESR1		D015029
CTD	increases(expression)			GSTM3		D015029
CTD	increases(expression)			JAG1		D015029
CTD	increases(expression)			MAOA		D015029
CTD	increases(expression)			MAPK1		D015029
CTD	increases(expression)			MAPK3		D015029
CTD	decreases(expression)			MIR34B		D015029
CTD	decreases(reaction)			NOS2		D015029
CTD	increases(expression)			NOS2		D015029
CTD	decreases(expression)			NOS3		D015029
CTD	decreases(reaction)			NOS3		D015029
CTD	increases(expression)			PRKCD		D015029
CTD	increases(expression)			SERPINA3		D015029
CTD	increases(expression)			SLC6A14		D015029
CTD	increases(expression)			TFF1		D015029
CTD	increases(expression)			TGFB3		D015029
PubChem	Ratio Potency (uM)	uM	11.044	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	16.293	AR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	19.570	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.856	AR	-	GI(Protien) :
PubChem	Potency	uM	7.308	ATAD5	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	61.566	CYP19A1	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	3.981	CYP3A4	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	Potency	uM	0.141	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.175	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.407	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.727	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	0.849	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	23.710	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	27.644	ESR1	-	GI(Protien) :
PubChem	None	uM		ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM		ESR1	-	GI(Protien) :
PubChem	AC50_uM	uM	87.540	GSK3A	-	GI(Protien) :
PubChem	IC50	uM	2.646	HSP90AA1	-	GI(Protien) :
PubChem	IC50	uM	27.927	HSP90AA1	-	GI(Protien) :
PubChem	None	uM		HSP90AA1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	46.572	HSPB1	-	GI(Protien) :
PubChem	EC50	uM		NOD1	-	GI(Protien) :
PubChem	None	uM		NR1H4	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	21.314	NR3C1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	39.186	NR3C1	-	GI(Protien) :
PubChem	None	uM		NR3C1	-	GI(Protien) :
PubChem	Potency	uM	14.581	TDP1	-	GI(Protien) :
PubChem	Potency	uM	18.356	TDP1	-	GI(Protien) :
ChEMBL	Potency	nM	7307.800	ATAD5	-	Target : CHEMBL1741209
ChEMBL	Potency	nM	3981.100	CYP3A4	-	Target : CHEMBL340
ChEMBL	IC50	nM	2646.200	HSP90AA1	-	Target : CHEMBL2095165
ChEMBL	IC50	nM	27927.100	HSP90AA1	-	Target : CHEMBL2095165
ChEMBL	IC50	nM	2646.200	HSP90AB1	-	Target : CHEMBL2095165
ChEMBL	IC50	nM	27927.100	HSP90AB1	-	Target : CHEMBL2095165

Download gene sets

gmt, text, Detailed text