Tan Lab | DSigDB

Gene Set: D4 : CTD - Yohimbine

Collection

D4 : CTD

Chemical Name

Yohimbine ( From PubChem : YOHIMBINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
354.443 g/mol	2	4	2.585	True

Structure

InChI

InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1

InChIKey

BLGXFZZNTVWLAY-SCYLSFHTSA-N

Links

Gene (18 / 35)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ABCB1		D015016
CTD	affects(binding)			ADRA2A		D015016
CTD	decreases(reaction)			ADRA2A		D015016
CTD	increases(activity)			ADRA2A		D015016
CTD	increases(reaction)			ADRA2A		D015016
CTD	decreases(reaction)			CGB		D015016
CTD	increases(abundance)			CGB		D015016
CTD	decreases(response to substance)			CGB		D015016
CTD	affects(metabolic processing)			CYP2D6		D015016
CTD	affects(metabolic processing)			CYP3A4		D015016
CTD	increases(expression)			PRL		D015016
PubChem	AhR Potency (uM)	uM	7.498	AHR	-	GI(Protien) :
PubChem	Potency	uM	17.783	DRD1	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	21.192	EHMT2	-	GI(Protien) :
PubChem	None	uM		HTR1A		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1B		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1D		GI(Protien) :
PubChem	None	uM		HTR1E		GI(Protien) :
PubChem	None	uM		HTR1F		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR2B		GI(Protien) :
PubChem	None	uM		HTR5A		GI(Protien) :
PubChem	None	uM		HTR7		GI(Protien) :
ChEMBL	Activity	-		ADRA2A	-	Target : CHEMBL1867
ChEMBL	Activity	-		ADRA2A	-	Target : CHEMBL1867
ChEMBL	Activity	-		ADRA2A	-	Target : CHEMBL1867
ChEMBL	Activity	-		ADRA2A	-	Target : CHEMBL1867
ChEMBL	Potency	nM	17782.800	DRD1	-	Target : CHEMBL2056
ChEMBL	Potency	nM	21192.300	EHMT2	-	Target : CHEMBL6032

Download gene sets

gmt, text, Detailed text