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Gene Set: D4 : CTD - Vinblastine

Collection D4 : CTD
Chemical Name Vinblastine ( From PubChem : VINBLASTINE )
FDA NPC WHO Indian Australia China Traditional
Herbal		 Clinical
Trail
NotNotNotNotNotNotNotNot
Molecular
Weight		 Hydrogen Bond
Donor Count		 Hydrogen Bond
Acceptor Count		 cLogP Lipinski Rule
810.974 g/mol 3 12 3.9317 False(2/4)
Structure
InChI InChI=1S/C46H58N4O9/c1-8-42(54)23-28-24-45(40(52)57-6,36-30(15-19-49(25-28)26-42)29-13-10-11-14-33(29)47-36)32-21-31-34(22-35(32)56-5)48(4)38-44(31)17-20-50-18-12-16-43(9-2,37(44)50)39(59-27(3)51)46(38,55)41(53)58-7/h10-14,16,21-22,28,37-39,47,54-55H,8-9,15,17-20,23-26H2,1-7H3/t28?,37?,38?,39-,42+,43-,44-,45+,46+/m1/s1
InChIKey JXLYSJRDGCGARV-BYEMHUETSA-N
Links

Gene (226 / 277)


⊖ Less
Source Type Unit Value Gene PMID Assay Other
CTDaffects(uptake)ABCB1
D014747
CTDdecreases(response to substance)ABCB1
D014747
CTDincreases(secretion)ABCB1
D014747
CTDincreases(transport)ABCB1
D014747
CTDdecreases(reaction)ABCB1
D014747
CTDdecreases(reaction)ABCB1
D014747
CTDincreases(transport)ABCB1
D014747
CTDdecreases(response to substance)ABCB1
D014747
CTDdecreases(reaction)ABCB1
D014747
CTDincreases(export)ABCB1
D014747
CTDaffects(reaction)ABCB1
D014747
CTDincreases(transport)ABCB1
D014747
CTDincreases(expression)ABCB1
D014747
CTDincreases(reaction)ABCB1
D014747
CTDdecreases(reaction)ABCB1
D014747
CTDdecreases(response to substance)ABCB1
D014747
CTDdecreases(response to substance)ABCB1
D014747
CTDincreases(expression)ABCB1
D014747
CTDdecreases(reaction)ABCB1
D014747
CTDdecreases(reaction)ABCB1
D014747
CTDincreases(activity)ABCB1
D014747
CTDincreases(activity)ABCB1
D014747
CTDdecreases(reaction)ABCB11
D014747
CTDincreases(transport)ABCB11
D014747
CTDdecreases(activity)ABCB11
D014747
CTDaffects(response to substance)ABCC1
D014747
CTDdecreases(response to substance)ABCC1
D014747
CTDaffects(transport)ABCC2
D014747
CTDaffects(transport)ABCC2
D014747
CTDincreases(reaction)ABCC2
D014747
CTDaffects(response to substance)ABLIM1
D014747
CTDaffects(response to substance)ACAT2
D014747
CTDaffects(response to substance)ACOT13
D014747
CTDaffects(response to substance)ACP1
D014747
CTDaffects(response to substance)ADD3
D014747
CTDaffects(response to substance)AOX1
D014747
CTDaffects(response to substance)APOBEC3C
D014747
CTDaffects(response to substance)ATP5I
D014747
CTDaffects(response to substance)ATP5J2
D014747
CTDaffects(response to substance)AURKB
D014747
CTDaffects(response to substance)AXL
D014747
CTDaffects(response to substance)BIRC2
D014747
CTDaffects(response to substance)BIRC3
D014747
CTDdecreases(response to substance)BIRC7
D014747
CTDaffects(response to substance)BUB1
D014747
CTDaffects(response to substance)C5ORF15
D014747
CTDdecreases(reaction)CASP3
D014747
CTDincreases(cleavage)CASP3
D014747
CTDincreases(reaction)CASP3
D014747
CTDaffects(response to substance)CAT
D014747
CTDaffects(response to substance)CCNB1
D014747
CTDincreases(response to substance)CCNB1
D014747
CTDaffects(response to substance)CCNB2
D014747
CTDdecreases(reaction)CD40LG
D014747
CTDincreases(cleavage)CD40LG
D014747
CTDincreases(reaction)CD40LG
D014747
CTDdecreases(response to substance)CD40LG
D014747
CTDaffects(response to substance)CDCA8
D014747
CTDaffects(response to substance)CDK1
D014747
CTDaffects(response to substance)CDK2
D014747
CTDaffects(response to substance)CDKN2C
D014747
CTDaffects(response to substance)CENPA
D014747
CTDaffects(response to substance)CKAP2
D014747
CTDaffects(response to substance)COX17
D014747
CTDaffects(response to substance)COX5A
D014747
CTDaffects(response to substance)COX6B1
D014747
CTDaffects(response to substance)CREG1
D014747
CTDaffects(response to substance)CRIPT
D014747
CTDaffects(response to substance)CTGF
D014747
CTDaffects(response to substance)CXCL5
D014747
CTDaffects(response to substance)CXCL8
D014747
CTDdecreases(reaction)CXCL8
D014747
CTDincreases(stability)CXCL8
D014747
CTDaffects(response to substance)DCPS
D014747
CTDaffects(response to substance)DDX23
D014747
CTDaffects(response to substance)DERA
D014747
CTDaffects(response to substance)DFFB
D014747
CTDaffects(response to substance)DKK1
D014747
CTDaffects(response to substance)DKK3
D014747
CTDaffects(response to substance)DONSON
D014747
CTDaffects(response to substance)DSCC1
D014747
CTDincreases(response to substance)E2F1
D014747
CTDaffects(response to substance)EFCAB7
D014747
CTDaffects(response to substance)EMP2
D014747
CTDaffects(response to substance)EPCAM
D014747
CTDaffects(response to substance)ERBB2
D014747
CTDaffects(response to substance)EREG
D014747
CTDaffects(response to substance)ETFB
D014747
CTDaffects(response to substance)EXOSC9
D014747
CTDaffects(response to substance)FAM3C
D014747
CTDaffects(response to substance)FAM69A
D014747
CTDaffects(response to substance)FANCL
D014747
CTDincreases(expression)FASLG
D014747
CTDaffects(response to substance)FEN1
D014747
CTDaffects(response to substance)FKBP1A
D014747
CTDaffects(response to substance)FLI1
D014747
CTDaffects(response to substance)FN1
D014747
CTDaffects(response to substance)FOSL1
D014747
CTDaffects(response to substance)G0S2
D014747
CTDaffects(response to substance)GGCT
D014747
CTDaffects(response to substance)GGCX
D014747
CTDaffects(response to substance)GMNN
D014747
CTDaffects(response to substance)GNPTAB
D014747
CTDaffects(response to substance)GPR176
D014747
CTDaffects(response to substance)GPSM2
D014747
CTDaffects(response to substance)GTF2I
D014747
CTDaffects(response to substance)GTF3A
D014747
CTDaffects(response to substance)GTSE1
D014747
CTDaffects(response to substance)GUSB
D014747
CTDaffects(response to substance)HADH
D014747
CTDaffects(response to substance)HCLS1
D014747
CTDaffects(response to substance)HIST1H1C
D014747
CTDaffects(response to substance)HMGB1
D014747
CTDaffects(response to substance)HMGB2
D014747
CTDaffects(response to substance)HMGN3
D014747
CTDaffects(response to substance)HMMR
D014747
CTDaffects(response to substance)HOMER1
D014747
CTDdecreases(expression)ICAM1
D014747
CTDaffects(response to substance)ID2
D014747
CTDaffects(response to substance)IDH2
D014747
CTDaffects(response to substance)IGF2BP3
D014747
CTDaffects(binding)IKBKB
D014747
CTDdecreases(localization)IKBKB
D014747
CTDincreases(phosphorylation)IKBKB
D014747
CTDaffects(response to substance)IL13RA2
D014747
CTDaffects(response to substance)IL1B
D014747
CTDdecreases(chemical synthesis)IL6
D014747
CTDincreases(stability)IL6
D014747
CTDaffects(response to substance)INHBA
D014747
CTDdecreases(expression)ITGAL
D014747
CTDaffects(response to substance)ITGB1BP1
D014747
CTDaffects(reaction)JUN
D014747
CTDincreases(phosphorylation)JUN
D014747
CTDaffects(response to substance)KANK1
D014747
CTDaffects(response to substance)KAZN
D014747
CTDaffects(response to substance)KIAA1598
D014747
CTDaffects(response to substance)KIF11
D014747
CTDaffects(response to substance)KIF15
D014747
CTDaffects(response to substance)KIF1B
D014747
CTDaffects(response to substance)KIF20A
D014747
CTDaffects(response to substance)KIF23
D014747
CTDaffects(response to substance)KIF4A
D014747
CTDaffects(response to substance)KPNA2
D014747
CTDaffects(response to substance)LMNB1
D014747
CTDaffects(response to substance)LPAR1
D014747
CTDaffects(response to substance)LRRC1
D014747
CTDaffects(response to substance)LSM7
D014747
CTDaffects(response to substance)LTBP2
D014747
CTDaffects(response to substance)MAD2L1
D014747
CTDaffects(reaction)MAPK8
D014747
CTDincreases(phosphorylation)MAPK8
D014747
CTDaffects(reaction)MAPK9
D014747
CTDincreases(phosphorylation)MAPK9
D014747
CTDaffects(response to substance)MAPKAPK5
D014747
CTDaffects(response to substance)MELK
D014747
CTDaffects(response to substance)MME
D014747
CTDaffects(response to substance)MMP1
D014747
CTDaffects(response to substance)MOK
D014747
CTDaffects(response to substance)MRPL57
D014747
CTDaffects(response to substance)MYC
D014747
CTDaffects(response to substance)MYCBP
D014747
CTDaffects(response to substance)NCAPG
D014747
CTDaffects(response to substance)NCAPH
D014747
CTDaffects(response to substance)NDC80
D014747
CTDaffects(response to substance)NDUFA1
D014747
CTDaffects(response to substance)NDUFA13
D014747
CTDaffects(response to substance)NDUFA3
D014747
CTDaffects(response to substance)NDUFA7
D014747
CTDaffects(response to substance)NDUFB2
D014747
CTDaffects(response to substance)NDUFC1
D014747
CTDaffects(response to substance)NDUFC2
D014747
CTDaffects(response to substance)NDUFS6
D014747
CTDaffects(response to substance)NDUFV2
D014747
CTDdecreases(localization)NFATC4
D014747
CTDaffects(binding)NFKBIA
D014747
CTDdecreases(localization)NFKBIA
D014747
CTDincreases(phosphorylation)NFKBIA
D014747
CTDincreases(expression)NR1I2
D014747
CTDincreases(reaction)NR1I2
D014747
CTDincreases(activity)NR1I2
D014747
CTDaffects(response to substance)NSMAF
D014747
CTDaffects(response to substance)NUDT15
D014747
CTDaffects(response to substance)NUDT4
D014747
CTDaffects(response to substance)NUSAP1
D014747
CTDaffects(response to substance)OAZ1
D014747
CTDaffects(response to substance)OIP5
D014747
CTDaffects(response to substance)OR10B1P
D014747
CTDaffects(response to substance)OR1I1
D014747
CTDaffects(response to substance)ORC6
D014747
CTDaffects(response to substance)OSBPL10
D014747
CTDdecreases(reaction)PARP1
D014747
CTDincreases(cleavage)PARP1
D014747
CTDincreases(reaction)PARP1
D014747
CTDaffects(response to substance)PDHB
D014747
CTDaffects(response to substance)PELO
D014747
CTDaffects(response to substance)PGRMC1
D014747
CTDaffects(response to substance)PIR
D014747
CTDaffects(response to substance)PLAU
D014747
CTDaffects(response to substance)PRC1
D014747
CTDaffects(response to substance)PSMB1
D014747
CTDaffects(response to substance)PSME4
D014747
CTDaffects(response to substance)PTGES3
D014747
CTDaffects(response to substance)PTTG1
D014747
CTDaffects(response to substance)PTX3
D014747
CTDincreases(phosphorylation)QRICH1
D014747
CTDaffects(response to substance)RAB11FIP1
D014747
CTDaffects(response to substance)RACGAP1
D014747
CTDaffects(response to substance)RANBP1
D014747
CTDaffects(response to substance)REV3L
D014747
CTDaffects(response to substance)RFC5
D014747
CTDaffects(response to substance)RPA3
D014747
CTDaffects(response to substance)RPS26P47
D014747
CTDaffects(response to substance)RRM2
D014747
CTDaffects(response to substance)SERPINB2
D014747
CTDaffects(response to substance)SERPINE1
D014747
CTDaffects(response to substance)SFXN1
D014747
CTDaffects(response to substance)SKP2
D014747
CTDaffects(response to substance)SLC22A3
D014747
CTDaffects(response to substance)SNRNP25
D014747
CTDaffects(response to substance)SNX10
D014747
CTDaffects(response to substance)SOD1
D014747
CTDaffects(response to substance)SORT1
D014747
CTDaffects(response to substance)SRD5A1
D014747
CTDaffects(response to substance)SRGN
D014747
CTDaffects(response to substance)STC2
D014747
CTDaffects(response to substance)STK26
D014747
CTDaffects(response to substance)STRN
D014747
CTDaffects(response to substance)SUCLA2
D014747
CTDaffects(response to substance)SUCLG1
D014747
CTDaffects(response to substance)SULT1A1
D014747
CTDaffects(response to substance)SYDE1
D014747
CTDaffects(response to substance)TBC1D4
D014747
CTDaffects(response to substance)TDG
D014747
CTDaffects(response to substance)TFPI2
D014747
CTDaffects(response to substance)TMEM134
D014747
CTDaffects(response to substance)TMEM14A
D014747
CTDaffects(response to substance)TMEM156
D014747
CTDaffects(response to substance)TMEM97
D014747
CTDaffects(response to substance)TMPO
D014747
CTDaffects(response to substance)TOP2A
D014747
CTDaffects(reaction)TP53
D014747
CTDincreases(phosphorylation)TP53
D014747
CTDaffects(response to substance)TPD52L1
D014747
CTDaffects(response to substance)TRIM2
D014747
CTDaffects(response to substance)TRMT5
D014747
CTDaffects(response to substance)TSPAN13
D014747
CTDaffects(response to substance)TTF2
D014747
CTDaffects(response to substance)TTK
D014747
CTDaffects(response to substance)UQCR10
D014747
CTDaffects(response to substance)VEGFC
D014747
CTDaffects(response to substance)WDR61
D014747
CTDaffects(response to substance)WSB2
D014747
CTDaffects(response to substance)YWHAQ
D014747
CTDaffects(response to substance)ZDHHC11
D014747
CTDaffects(response to substance)ZFP36L2
D014747
CTDaffects(response to substance)ZWINT
D014747
PubChem NoneuMSTK33-GI(Protien) :
PubChem PotencyuM0.750GMNN-GI(Protien) :
PubChem PotencyuM0.071TDP1-GI(Protien) :
PubChem PotencyuM0.141TDP1-GI(Protien) :
ChEMBLActivity-ABCB1
-Target : CHEMBL4302
ChEMBLInhibition-ABCB1
-Target : CHEMBL4302
ChEMBLInhibition-TUBA1A
-Target : CHEMBL2095182
ChEMBLInhibition-TUBA1B
-Target : CHEMBL2095182
ChEMBLInhibition-TUBA1C
-Target : CHEMBL2095182
ChEMBLInhibition-TUBA3C; TUBA3D
-Target : CHEMBL2095182
ChEMBLInhibition-TUBA3E
-Target : CHEMBL2095182
ChEMBLInhibition-TUBA4A
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB1
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB2A
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB2B
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB3
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB4A
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB4B
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB6
-Target : CHEMBL2095182
ChEMBLInhibition-TUBB8
-Target : CHEMBL2095182
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University of Colorado School of Medicine
Aurora, CO 80045, USA

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