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Gene Set: D4 : CTD - Ursodeoxycholic Acid

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Collection	D4 : CTD
Chemical Name	Ursodeoxycholic Acid ( From PubChem : URSODIOL )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Not Approved Approved Not Approved Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 392.572 g/mol 3 4 4.4779 True
Structure
InChI	InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1
InChIKey	RUDATBOHQWOJDD-UZVSRGJWSA-N
Links
Gene (138 / 289) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD increases(expression) ABCB1 D014580 CTD increases(expression) ABCB11 D014580 CTD decreases(reaction) ABCC1 D014580 CTD increases(export) ABCC1 D014580 CTD increases(expression) ABCC2 D014580 CTD increases(expression) ABCC2 D014580 CTD decreases(activity) AKR1C1 D014580 CTD affects(cotreatment) AKR1C2 D014580 CTD decreases(reaction) AKR1C2 D014580 CTD increases(reduction) AKR1C2 D014580 CTD decreases(activity) AKR1C2 D014580 CTD decreases(activity) AKR1C3 D014580 CTD decreases(reaction) AKT1 D014580 CTD increases(phosphorylation) AKT1 D014580 CTD affects(expression) ANKRD28 D014580 CTD affects(expression) AP2M1 D014580 CTD increases(expression) APOA1 D014580 CTD decreases(reaction) APOM D014580 CTD increases(expression) APOM D014580 CTD decreases(expression) ATF4 D014580 CTD affects(localization) BAX D014580 CTD decreases(reaction) BAX D014580 CTD increases(expression) BAX D014580 CTD increases(expression) BAX D014580 CTD decreases(expression) BCL2 D014580 CTD increases(expression) BLVRA D014580 CTD affects(expression) C4BPA D014580 CTD affects(cotreatment) CASP3 D014580 CTD decreases(reaction) CASP3 D014580 CTD increases(activity) CASP3 D014580 CTD decreases(reaction) CASP3 D014580 CTD increases(activity) CASP3 D014580 CTD increases(cleavage) CASP3 D014580 CTD decreases(reaction) CASP3 D014580 CTD increases(activity) CASP3 D014580 CTD decreases(reaction) CASP3 D014580 CTD increases(activity) CASP3 D014580 CTD increases(activity) CASP3 D014580 CTD increases(reaction) CASP3 D014580 CTD decreases(reaction) CASP6 D014580 CTD increases(activity) CASP6 D014580 CTD increases(cleavage) CASP6 D014580 CTD decreases(reaction) CASP7 D014580 CTD increases(activity) CASP7 D014580 CTD decreases(reaction) CASP7 D014580 CTD increases(activity) CASP7 D014580 CTD decreases(reaction) CASP8 D014580 CTD increases(activity) CASP8 D014580 CTD affects(cotreatment) CASP8 D014580 CTD increases(activity) CASP8 D014580 CTD increases(cleavage) CASP8 D014580 CTD decreases(reaction) CASP8 D014580 CTD increases(activity) CASP8 D014580 CTD increases(reaction) CASP8 D014580 CTD decreases(reaction) CASP9 D014580 CTD increases(activity) CASP9 D014580 CTD decreases(reaction) CCL2 D014580 CTD increases(expression) CCL2 D014580 CTD increases(reaction) CCL2 D014580 CTD increases(expression) CCL2 D014580 CTD decreases(reaction) CCL5 D014580 CTD increases(expression) CCL5 D014580 CTD increases(reaction) CCL5 D014580 CTD decreases(expression) CCND1 D014580 CTD decreases(expression) CCND3 D014580 CTD affects(expression) CCT3 D014580 CTD affects(expression) CCT5 D014580 CTD affects(expression) CD248 D014580 CTD decreases(reaction) CEBPB D014580 CTD increases(expression) CEBPB D014580 CTD increases(expression) CFLAR D014580 CTD affects(expression) CNP D014580 CTD affects(expression) CSE1L D014580 CTD affects(expression) CSPG4 D014580 CTD increases(expression) CXCL1 D014580 CTD affects(cotreatment) CXCL8 D014580 CTD decreases(reaction) CXCL8 D014580 CTD increases(secretion) CXCL8 D014580 CTD increases(expression) CXCL8 D014580 CTD increases(reaction) CXCL8 D014580 CTD decreases(reaction) CYP1A1 D014580 CTD increases(expression) CYP1A1 D014580 CTD affects(metabolic processing) CYP3A4 D014580 CTD increases(abundance) CYP3A4 D014580 CTD increases(metabolic processing) CYP3A4 D014580 CTD increases(expression) CYP3A4 D014580 CTD decreases(expression) CYP7A1 D014580 CTD increases(reaction) CYP7A1 D014580 CTD decreases(expression) CYP7A1 D014580 CTD affects(expression) DAP3 D014580 CTD affects(expression) DHX9 D014580 CTD affects(expression) DLAT D014580 CTD decreases(activity) DLC1 D014580 CTD decreases(reaction) DLC1 D014580 CTD increases(expression) DLC1 D014580 CTD decreases(expression) DNAJC3 D014580 CTD decreases(expression) EDN1 D014580 CTD decreases(expression) EDN2 D014580 CTD decreases(reaction) EGFR D014580 CTD increases(phosphorylation) EGFR D014580 CTD affects(expression) EIF1 D014580 CTD affects(binding) EP300 D014580 CTD affects(cotreatment) EP300 D014580 CTD increases(reaction) EP300 D014580 CTD affects(expression) ERMP1 D014580 CTD decreases(expression) FABP4 D014580 CTD decreases(reaction) FABP6 D014580 CTD increases(expression) FABP6 D014580 CTD decreases(reaction) FADD D014580 CTD increases(activity) FADD D014580 CTD increases(cleavage) FADD D014580 CTD affects(expression) FAM169A D014580 CTD affects(expression) FAM35A D014580 CTD decreases(expression) FASN D014580 CTD increases(expression) FGF19 D014580 CTD increases(reaction) FGF19 D014580 CTD affects(expression) FGG D014580 CTD affects(expression) FGL1 D014580 CTD affects(expression) GARS D014580 CTD decreases(reaction) GCLC D014580 CTD increases(expression) GCLC D014580 CTD affects(expression) GCLC D014580 CTD decreases(reaction) GCLC D014580 CTD increases(reaction) GCLC D014580 CTD decreases(expression) GCLC D014580 CTD decreases(reaction) GCLM D014580 CTD increases(expression) GCLM D014580 CTD decreases(expression) GCLM D014580 CTD decreases(expression) GPBAR1 D014580 CTD decreases(reaction) GSS D014580 CTD increases(expression) GSS D014580 CTD affects(expression) GSS D014580 CTD decreases(reaction) GSS D014580 CTD increases(reaction) GSS D014580 CTD decreases(expression) GSS D014580 CTD decreases(reaction) HGF D014580 CTD increases(expression) HGF D014580 CTD affects(cotreatment) HLA-DRA D014580 CTD decreases(expression) HLA-DRA D014580 CTD decreases(reaction) HLA-DRA D014580 CTD increases(expression) HLA-DRA D014580 CTD affects(binding) HNF1A D014580 CTD affects(cotreatment) HNF1A D014580 CTD increases(reaction) HNF1A D014580 CTD affects(binding) HNF1B D014580 CTD affects(cotreatment) HNF1B D014580 CTD increases(reaction) HNF1B D014580 CTD increases(chemical synthesis) HSD11B1 D014580 CTD increases(reduction) HSD11B1 D014580 CTD decreases(expression) HSPA5 D014580 CTD affects(expression) ICAM3 D014580 CTD decreases(reaction) IFNG D014580 CTD increases(expression) IFNG D014580 CTD decreases(reaction) IL6 D014580 CTD increases(expression) IL6 D014580 CTD increases(reaction) IL6 D014580 CTD increases(secretion) IL6 D014580 CTD affects(expression) IMPDH2 D014580 CTD decreases(expression) IVL D014580 CTD decreases(reaction) MAF D014580 CTD increases(expression) MAF D014580 CTD increases(reaction) MAF D014580 CTD decreases(reaction) MAFG D014580 CTD increases(expression) MAFG D014580 CTD increases(reaction) MAFG D014580 CTD decreases(reaction) MAPK1 D014580 CTD increases(phosphorylation) MAPK1 D014580 CTD decreases(reaction) MAPK1 D014580 CTD increases(activity) MAPK1 D014580 CTD increases(phosphorylation) MAPK1 D014580 CTD decreases(reaction) MAPK3 D014580 CTD increases(phosphorylation) MAPK3 D014580 CTD decreases(reaction) MAPK3 D014580 CTD increases(activity) MAPK3 D014580 CTD increases(phosphorylation) MAPK3 D014580 CTD affects(expression) MBP D014580 CTD increases(expression) MCL1 D014580 CTD decreases(reaction) MDM2 D014580 CTD increases(ubiquitination) MDM2 D014580 CTD increases(expression) MIR21 D014580 CTD affects(expression) NAP1L1 D014580 CTD affects(expression) NEAT1 D014580 CTD decreases(reaction) NFE2L2 D014580 CTD increases(localization) NFE2L2 D014580 CTD decreases(expression) NFE2L2 D014580 CTD decreases(reaction) NFE2L2 D014580 CTD increases(reaction) NFE2L2 D014580 CTD decreases(reaction) NFKB1 D014580 CTD increases(expression) NFKB1 D014580 CTD increases(reaction) NFKB1 D014580 CTD increases(expression) NR0B2 D014580 CTD affects(binding) NR1H4 D014580 CTD decreases(reaction) NR1H4 D014580 CTD decreases(expression) NR1H4 D014580 CTD increases(activity) NR1H4 D014580 CTD increases(expression) NR1H4 D014580 CTD increases(expression) NR1H4 D014580 CTD increases(expression) NR1I2 D014580 CTD affects(localization) NR3C1 D014580 CTD affects(binding) NR3C1 D014580 CTD affects(cotreatment) NR3C1 D014580 CTD increases(reaction) NR3C1 D014580 CTD increases(localization) NR3C1 D014580 CTD affects(cotreatment) NR3C1 D014580 CTD decreases(expression) NR3C1 D014580 CTD increases(localization) NR3C1 D014580 CTD affects(expression) OAF D014580 CTD affects(expression) ORM2 D014580 CTD decreases(reaction) PARP1 D014580 CTD increases(cleavage) PARP1 D014580 CTD affects(cotreatment) PARP1 D014580 CTD increases(cleavage) PARP1 D014580 CTD decreases(expression) PPARG D014580 CTD increases(activity) PRKCB D014580 CTD decreases(reaction) PRKCD D014580 CTD increases(localization) PRKCD D014580 CTD increases(response to substance) PRKCD D014580 CTD decreases(reaction) PTGS2 D014580 CTD increases(expression) PTGS2 D014580 CTD decreases(reaction) RAC1 D014580 CTD increases(expression) RAC1 D014580 CTD affects(expression) RAC1 D014580 CTD decreases(reaction) RAF1 D014580 CTD increases(activity) RAF1 D014580 CTD increases(phosphorylation) RAF1 D014580 CTD decreases(expression) RB1 D014580 CTD affects(expression) RBBP6 D014580 CTD affects(expression) RFFL D014580 CTD decreases(activity) RHOA D014580 CTD decreases(reaction) RHOA D014580 CTD affects(expression) RHOBTB3 D014580 CTD decreases(reaction) RIPK1 D014580 CTD increases(activity) RIPK1 D014580 CTD increases(cleavage) RIPK1 D014580 CTD affects(expression) RPL10 D014580 CTD affects(expression) RPL27 D014580 CTD affects(expression) RPL32 D014580 CTD affects(expression) RPL35A D014580 CTD affects(expression) RPL39L D014580 CTD affects(expression) RPL6 D014580 CTD affects(expression) RPLP2 D014580 CTD affects(expression) RPS13 D014580 CTD affects(expression) RPS27L D014580 CTD affects(expression) RPS28 D014580 CTD affects(expression) RPS3AP6 D014580 CTD affects(expression) SAMD4B D014580 CTD decreases(expression) SCD D014580 CTD affects(expression) SF3B1 D014580 CTD increases(expression) SLC23A1 D014580 CTD increases(expression) SLC23A2 D014580 CTD affects(expression) SLC25A5 D014580 CTD decreases(reaction) SLC27A5 D014580 CTD increases(uptake) SLC27A5 D014580 CTD affects(binding) SLC4A2 D014580 CTD affects(cotreatment) SLC4A2 D014580 CTD increases(reaction) SLC4A2 D014580 CTD increases(activity) SLC4A2 D014580 CTD increases(expression) SLC4A2 D014580 CTD increases(uptake) SLCO1B1 D014580 CTD increases(uptake) SLCO1B3 D014580 CTD affects(expression) SPRY4 D014580 CTD affects(expression) SSBP1 D014580 CTD affects(cotreatment) STAT1 D014580 CTD increases(activity) STAT1 D014580 CTD affects(expression) STK3 D014580 CTD increases(sulfation) SULT2A1 D014580 CTD affects(cotreatment) TNF D014580 CTD decreases(reaction) TNF D014580 CTD increases(secretion) TNF D014580 CTD increases(expression) TNF D014580 CTD increases(reaction) TNF D014580 CTD increases(activity) TNF D014580 CTD affects(cotreatment) TNFAIP3 D014580 CTD increases(expression) TNFAIP3 D014580 CTD increases(reaction) TNFAIP3 D014580 CTD decreases(reaction) TNFRSF10B D014580 CTD increases(expression) TNFRSF10B D014580 CTD increases(activity) TNFRSF10B D014580 CTD increases(cleavage) TNFRSF10B D014580 CTD increases(response to substance) TNFRSF10B D014580 CTD decreases(reaction) TP53 D014580 CTD increases(ubiquitination) TP53 D014580 CTD affects(cotreatment) TP53 D014580 CTD decreases(reaction) TP53 D014580 CTD increases(activity) TP53 D014580 CTD affects(expression) WDR33 D014580 PubChem None uM WEE1 - GI(Protien) : ChEMBL Activity - NR3C1 - Target : CHEMBL2034 ChEMBL Activity - NR3C1 - Target : CHEMBL2034
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