Tan Lab | DSigDB

Gene Set: D4 : CTD - Tyramine

Collection

D4 : CTD

Chemical Name

Tyramine ( From PubChem : TYRAMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
137.179 g/mol	2	2	1.5937	True

Structure

InChI

InChI=1S/C8H11NO/c9-6-5-7-1-3-8(10)4-2-7/h1-4,10H,5-6,9H2

InChIKey

Links

Gene (10 / 26)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(metabolic processing)			MAOA		D014439
CTD	decreases(reaction)			SLC6A2		D014439
CTD	increases(activity)			SLC6A2		D014439
CTD	increases(reaction)			SLC6A2		D014439
CTD	decreases(reaction)			SLC6A3		D014439
CTD	increases(activity)			SLC6A3		D014439
CTD	increases(reaction)			SLC6A3		D014439
CTD	decreases(reaction)			SLC6A4		D014439
CTD	increases(activity)			SLC6A4		D014439
CTD	increases(reaction)			SLC6A4		D014439
CTD	increases(sulfation)			SULT1A3		D014439
CTD	decreases(reaction)			TAAR1		D014439
CTD	increases(activity)			TAAR1		D014439
CTD	increases(reaction)			TAAR1		D014439
PubChem	Potency	uM	8.200	DRD1	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD2	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	EC50	uM	0.178	TAAR1	-	GI(Protien) :
PubChem	IC50	uM	0.882	TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
ChEMBL	Activity	-		HTR3A	-	Target : CHEMBL1899

Download gene sets