Tan Lab | DSigDB

Gene Set: D4 : CTD - Triprolidine

Collection

D4 : CTD

Chemical Name

Triprolidine ( From PubChem : TRIPROLIDINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Approved	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
278.391 g/mol	0	2	3.8554	True

Structure

InChI

InChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3/b18-11+

InChIKey

Links

Gene (10 / 37)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			CD14		D014311
CTD	affects(binding)			CD40		D014311
CTD	decreases(expression)			CD40		D014311
CTD	decreases(reaction)			CD40		D014311
CTD	increases(activity)			CD40		D014311
CTD	decreases(response to substance)			CXCL8		D014311
CTD	increases(reaction)			CXCL8		D014311
CTD	decreases(response to substance)			HRH1		D014311
CTD	increases(reaction)			HRH1		D014311
CTD	affects(binding)			HRH1		D014311
CTD	decreases(activity)			HRH1		D014311
CTD	affects(binding)			HRH1		D014311
CTD	increases(activity)			HRH1		D014311
CTD	affects(binding)			HRH1		D014311
CTD	decreases(reaction)			HRH1		D014311
CTD	increases(activity)			HRH1		D014311
CTD	decreases(expression)			HRH1		D014311
CTD	decreases(reaction)			HRH1		D014311
CTD	increases(abundance)			HRH1		D014311
CTD	increases(activity)			HRH1		D014311
CTD	decreases(abundance)			HRH1		D014311
CTD	decreases(reaction)			HRH1		D014311
CTD	increases(reaction)			HRH1		D014311
CTD	increases(export)			HRH1		D014311
CTD	increases(metabolic processing)			HRH1		D014311
CTD	affects(binding)			HRH1		D014311
CTD	decreases(reaction)			HRH1		D014311
CTD	decreases(expression)			ITGA4		D014311
CTD	decreases(expression)			ITGAX		D014311
CTD	decreases(expression)			LRP1		D014311
CTD	affects(binding)			PTPRC		D014311
CTD	decreases(expression)			PTPRC		D014311
CTD	decreases(reaction)			PTPRC		D014311
CTD	increases(activity)			PTPRC		D014311
PubChem	Potency	uM	7.519	EHMT2	-	GI(Protien) :
ChEMBL	Potency	nM	7519.300	EHMT2	-	Target : CHEMBL6032
ChEMBL	Potency	nM	14581.000	NFE2L2	-	Target : CHEMBL1075094

Download gene sets