Tan Lab | DSigDB

Gene Set: D4 : CTD - Trientine

Collection

D4 : CTD

Chemical Name

Trientine ( From PubChem : TRIETHYLENETETRAMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
146.234 g/mol	4	4	0.2654	True

Structure

InChI

InChI=1S/C6H18N4/c7-1-3-9-5-6-10-4-2-8/h9-10H,1-8H2

InChIKey

Links

Gene (8 / 33)

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Source	Type	Gene	Other
CTD	affects(binding)	APP	D014266
CTD	affects(cotreatment)	APP	D014266
CTD	decreases(reaction)	APP	D014266
CTD	increases(chemical synthesis)	APP	D014266
CTD	increases(oxidation)	APP	D014266
CTD	decreases(reaction)	APP	D014266
CTD	increases(activity)	APP	D014266
CTD	increases(metabolic processing)	APP	D014266
CTD	decreases(reaction)	BCL2	D014266
CTD	increases(expression)	BCL2	D014266
CTD	decreases(expression)	BCL2	D014266
CTD	increases(activity)	CASP3	D014266
CTD	increases(reaction)	CASP3	D014266
CTD	decreases(reaction)	CASP3	D014266
CTD	increases(activity)	CASP3	D014266
CTD	increases(activity)	CASP3	D014266
CTD	increases(activity)	CASP9	D014266
CTD	decreases(reaction)	CXCL8	D014266
CTD	increases(expression)	CXCL8	D014266
CTD	decreases(activity)	CXCL8	D014266
CTD	decreases(expression)	CXCL8	D014266
CTD	decreases(activity)	SOD1	D014266
CTD	decreases(reaction)	SOD1	D014266
CTD	decreases(abundance)	SOD1	D014266
CTD	decreases(activity)	SOD1	D014266
CTD	decreases(activity)	SOD1	D014266
CTD	decreases(expression)	SOD1	D014266
CTD	increases(activity)	SOD2	D014266
CTD	increases(expression)	SOD2	D014266
CTD	increases(phosphorylation)	TP53	D014266
CTD	increases(reaction)	TP53	D014266
CTD	increases(activity)	TP53	D014266
CTD	increases(expression)	TP53	D014266

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