Tan Lab | DSigDB

Gene Set: D4 : CTD - Trichlorfon

Collection

D4 : CTD

Chemical Name

Trichlorfon ( From PubChem : METRIFONATE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Approved	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
257.437 g/mol	1	4	2.1609	True

Structure

InChI

InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3/t3-/m0/s1

InChIKey

Links

Gene (15 / 34)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(activity)			ACHE		D014236
CTD	decreases(reaction)			ACHE		D014236
CTD	decreases(activity)			ACHE		D014236
CTD	decreases(reaction)			ACHE		D014236
CTD	affects(cotreatment)			ACHE		D014236
CTD	decreases(activity)			ACHE		D014236
CTD	decreases(activity)			ACHE		D014236
CTD	increases(secretion)			APP		D014236
CTD	decreases(activity)			BCHE		D014236
CTD	decreases(reaction)			BCHE		D014236
CTD	decreases(activity)			BCHE		D014236
CTD	decreases(expression)			BCL2		D014236
CTD	decreases(reaction)			BCL2		D014236
CTD	decreases(reaction)			CASP12		D014236
CTD	increases(activity)			CASP12		D014236
CTD	increases(cleavage)			CASP12		D014236
CTD	affects(cotreatment)			CASP12		D014236
CTD	decreases(reaction)			CASP3		D014236
CTD	increases(activity)			CASP3		D014236
CTD	increases(cleavage)			CASP3		D014236
CTD	affects(cotreatment)			CASP3		D014236
CTD	decreases(activity)			CAT		D014236
CTD	increases(activity)			CAT		D014236
CTD	decreases(reaction)			FSHB		D014236
CTD	increases(abundance)			FSHB		D014236
CTD	increases(activity)			HNF4A		D014236
CTD	increases(activity)			NFE2L2		D014236
CTD	decreases(activity)			PNPLA6		D014236
CTD	decreases(expression)			SERPINA3		D014236
CTD	decreases(expression)			STAR		D014236
CTD	increases(expression)			TP53		D014236
PubChem	None	uM		GSTO1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.230	NFE2L2	-	GI(Protien) :
PubChem	Potency	uM	19.331	NFE2L2	-	GI(Protien) :

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