Tan Lab | DSigDB

Gene Set: D4 : CTD - Triazolam

Collection

D4 : CTD

Chemical Name

Triazolam ( From PubChem : TRIAZOLAM )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Approved	Not	Not	Not	Not	Not	Not	4

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
343.21 g/mol	0	4	3.6691	True

Structure

InChI

InChI=1S/C17H12Cl2N4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3

InChIKey

Links

Gene (12 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(metabolic processing)			CYP3A4		D014229
CTD	decreases(reaction)			CYP3A4		D014229
CTD	increases(metabolic processing)			CYP3A4		D014229
CTD	decreases(reaction)			CYP3A4		D014229
CTD	increases(hydroxylation)			CYP3A4		D014229
CTD	increases(oxidation)			CYP3A4		D014229
CTD	increases(reaction)			CYP3A4		D014229
CTD	decreases(reaction)			SLC22A2		D014229
CTD	increases(uptake)			SLC22A2		D014229
CTD	decreases(reaction)			SLC22A6		D014229
CTD	increases(uptake)			SLC22A6		D014229
PubChem	Potency-Replicate_1	uM	33.492	ESR1	-	GI(Protien) :
PubChem	ER Potency (uM)	uM	33.492	ESR1	-	GI(Protien) :
ChEMBL	Activity	-		BAZ2B	-	Target : CHEMBL1741220
ChEMBL	Activity	-		BRD2	-	Target : CHEMBL1293289
ChEMBL	Activity	-		BRD2	-	Target : CHEMBL1293289
ChEMBL	Activity	-		BRD3	-	Target : CHEMBL1795186
ChEMBL	Activity	-		BRD3	-	Target : CHEMBL1795186
ChEMBL	Activity	-		BRD4	-	Target : CHEMBL1163125
ChEMBL	Activity	-		BRD4	-	Target : CHEMBL1163125
ChEMBL	Activity	-		BRDT	-	Target : CHEMBL1795185
ChEMBL	Activity	-		CREBBP	-	Target : CHEMBL5747
ChEMBL	Activity	-		KAT2B	-	Target : CHEMBL5500
ChEMBL	Activity	-		PBRM1	-	Target : CHEMBL1795184

Download gene sets