DSigDB

Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

Home

Search Gene

Collection

Browse

Download

Help

DSigDB Home

Search Gene

Collections

Browse Gene Sets

Download

Help

Gene Set: D4 : CTD - Triamcinolone Acetonide

---

Collection	D4 : CTD
Chemical Name	Triamcinolone Acetonide ( From PubChem : TRIAMCINOLONE ACETONIDE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Approved Not Not Approved Not Approved Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 434.498 g/mol 2 6 2.4188 True
Structure
InChI	InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChIKey	YNDXUCZADRHECN-JNQJZLCISA-N
Links
Gene (20 / 58) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) CCL5 D014222 CTD increases(secretion) CCL5 D014222 CTD decreases(reaction) CSF2 D014222 CTD increases(secretion) CSF2 D014222 CTD decreases(secretion) CSF2 D014222 CTD increases(expression) CTGF D014222 CTD increases(reaction) CTGF D014222 CTD decreases(expression) CYP2S1 D014222 CTD decreases(reaction) IL1B D014222 CTD increases(abundance) IL1B D014222 CTD increases(expression) IL1B D014222 CTD decreases(reaction) IL1B D014222 CTD increases(secretion) IL1B D014222 CTD decreases(expression) MKI67 D014222 CTD affects(binding) NR3C1 D014222 CTD affects(localization) NR3C1 D014222 CTD affects(binding) NR3C1 D014222 CTD affects(binding) NR3C1 D014222 CTD decreases(secretion) NR3C1 D014222 CTD decreases(expression) NR3C1 D014222 CTD decreases(activity) PLA2G4A D014222 CTD decreases(reaction) SLC22A2 D014222 CTD increases(uptake) SLC22A2 D014222 CTD decreases(reaction) TGFB1 D014222 CTD increases(expression) TGFB1 D014222 CTD decreases(reaction) TNF D014222 CTD increases(expression) TNF D014222 CTD decreases(reaction) TNF D014222 CTD increases(expression) TNF D014222 CTD decreases(reaction) TNF D014222 CTD increases(secretion) TNF D014222 CTD decreases(reaction) VCAM1 D014222 CTD increases(expression) VCAM1 D014222 CTD affects(binding) VEGFA D014222 CTD decreases(secretion) VEGFA D014222 CTD decreases(reaction) VEGFA D014222 CTD increases(expression) VEGFA D014222 CTD increases(secretion) VEGFA D014222 CTD decreases(reaction) VEGFA D014222 CTD increases(expression) VEGFA D014222 CTD decreases(expression) VEGFA D014222 PubChem None uM ABCC1 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.002 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.005 AR - GI(Protien) : PubChem Potency-Replicate_1 uM 0.007 AR - GI(Protien) : PubChem None uM CFTR - GI(Protien) : PubChem None uM CHRM4 - GI(Protien) : PubChem Potency-Replicate_1 uM 2.371 ESR1 - GI(Protien) : PubChem Potency-Replicate_1 uM 11.986 ESR1 - GI(Protien) : PubChem Ratio Potency (uM) uM 22.992 ESR1 - GI(Protien) : PubChem Ratio Potency (uM) uM HSPB1 - GI(Protien) : PubChem Potency uM 0.004 NFE2L2 - GI(Protien) : PubChem Potency-Replicate_1 uM 0.001 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.002 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.002 NR3C1 - GI(Protien) : PubChem Ratio Potency (uM) uM 0.005 NR3C1 - GI(Protien) : PubChem None uM NR3C1 - GI(Protien) : ChEMBL Potency nM 4.100 NFE2L2 - Target : CHEMBL1075094
Download gene sets	gmt, text, Detailed text

Contact us
Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

* Best viewed in the latest version of Chrome (42+), Safari (8+), IE (11+) or Firefox (35+).