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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Tosyllysine Chloromethyl Ketone

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Collection	D4 : CTD
Chemical Name	Tosyllysine Chloromethyl Ketone ( From PubChem : TOSYLLYSYL CHLOROMETHANE )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 332.846 g/mol 2 5 3.7508 True
Structure
InChI	InChI=1S/C14H21ClN2O3S/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16/h5-8,13,17H,2-4,9-10,16H2,1H3/t13-/m0/s1
InChIKey	RDFCSSHDJSZMTQ-ZDUSSCGKSA-N
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Gene (17 / 39) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) CCL2 D014107 CTD increases(expression) CCL2 D014107 CTD decreases(reaction) CX3CL1 D014107 CTD increases(expression) CX3CL1 D014107 CTD decreases(reaction) CXCL1 D014107 CTD increases(expression) CXCL1 D014107 CTD decreases(reaction) CXCL8 D014107 CTD increases(expression) CXCL8 D014107 CTD decreases(reaction) CXCL8 D014107 CTD increases(expression) CXCL8 D014107 CTD decreases(reaction) CYP2E1 D014107 CTD increases(degradation) CYP2E1 D014107 CTD decreases(reaction) FGF2 D014107 CTD increases(expression) FGF2 D014107 CTD decreases(reaction) ICAM1 D014107 CTD increases(expression) ICAM1 D014107 CTD decreases(reaction) IRF1 D014107 CTD increases(expression) IRF1 D014107 CTD decreases(reaction) ITGAM D014107 CTD increases(localization) ITGAM D014107 CTD decreases(reaction) NFKB1 D014107 CTD increases(activity) NFKB1 D014107 CTD decreases(reaction) NFKBIA D014107 CTD increases(degradation) NFKBIA D014107 CTD decreases(reaction) NRP1 D014107 CTD increases(expression) NRP1 D014107 CTD decreases(reaction) RELA D014107 CTD increases(activity) RELA D014107 CTD decreases(phosphorylation) RPS6KB1 D014107 CTD decreases(reaction) RPS6KB1 D014107 CTD decreases(reaction) TGM2 D014107 CTD increases(activity) TGM2 D014107 CTD increases(expression) TGM2 D014107 CTD decreases(reaction) TNF D014107 CTD increases(degradation) TNF D014107 CTD increases(expression) TNF D014107 CTD increases(expression) TNF D014107 CTD decreases(reaction) VCAM1 D014107 CTD increases(expression) VCAM1 D014107
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