Tan Lab | DSigDB

Gene Set: D4 : CTD - 4-methyl-7-diethylaminocoumarin

Collection

D4 : CTD

Chemical Name

4-methyl-7-diethylaminocoumarin ( From PubChem : 7-DIETHYLAMINO-4-METHYLCOUMARIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
231.29 g/mol	0	3	2.9476	True

Structure

InChI

InChI=1S/C14H17NO2/c1-4-15(5-2)11-6-7-12-10(3)8-14(16)17-13(12)9-11/h6-9H,4-5H2,1-3H3

InChIKey

Links

Gene (18 / 27)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			AKAP9		C002166
CTD	increases(expression)			ANKRD37		C002166
CTD	increases(activity)			HIF1A		C002166
CTD	increases(expression)			PFKM		C002166
CTD	increases(expression)			PSPH		C002166
CTD	increases(expression)			VEGFA		C002166
PubChem	AhR Potency (uM)	uM	17.229	AHR	-	GI(Protien) :
PubChem	AR Potency (uM)	uM	4.328	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	15.480	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	24.544	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.638	AR	-	GI(Protien) :
PubChem	Potency	uM	39.811	AR	-	GI(Protien) :
PubChem	Potency	uM	31.623	ATM	-	GI(Protien) :
PubChem	None	uM		GFER	-	GI(Protien) :
PubChem	Potency	uM	25.929	GMNN	-	GI(Protien) :
PubChem	Potency	uM	44.668	HIF1A	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	13.914	HSPB1	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	None	uM		KLK7	-	GI(Protien) :
PubChem	Potency	uM	37.578	NFE2L2	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	14.125	NR1I2	-	GI(Protien) :
PubChem	Potency	uM	22.387	THRB	-	GI(Protien) :
PubChem	Potency	uM	44.668	VDR	-	GI(Protien) :
ChEMBL	Potency	nM	31622.800	ATM	-	Target : CHEMBL3797
ChEMBL	Potency	nM	44668.400	HIF1A	-	Target : CHEMBL4261
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159
ChEMBL	Potency	nM	31622.800	HSD17B10	-	Target : CHEMBL4159

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