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Drug SIGnatures DataBase Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt

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Collection	D4 : CTD
Chemical Name	1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt ( From PubChem : TIRON )
FDA NPC WHO Indian Australia China Traditional Herbal Clinical Trail Not Not Not Not Not Not Not Not
Molecular Weight Hydrogen Bond Donor Count Hydrogen Bond Acceptor Count cLogP Lipinski Rule 314.201 g/mol 2 8 1.0676 True
Structure
InChI	InChI=1S/C6H6O8S2.2Na/c7-4-1-3(15(9,10)11)2-5(6(4)8)16(12,13)14;;/h1-2,7-8H,(H,9,10,11)(H,12,13,14);;/q;2*+1/p-2
InChIKey	ISWQCIVKKSOKNN-UHFFFAOYSA-L
Links
Gene (31 / 74) ⊖ Less	Source Type Unit Value Gene PMID Assay Other CTD decreases(reaction) AGT D014013 CTD increases(phosphorylation) AGT D014013 CTD increases(reaction) AGT D014013 CTD decreases(reaction) ATF4 D014013 CTD increases(expression) ATF4 D014013 CTD decreases(reaction) BAD D014013 CTD increases(expression) BAD D014013 CTD decreases(reaction) BAX D014013 CTD increases(expression) BAX D014013 CTD decreases(expression) BCL2 D014013 CTD decreases(reaction) BCL2 D014013 CTD decreases(reaction) BECN1 D014013 CTD increases(expression) BECN1 D014013 CTD affects(reaction) CASP3 D014013 CTD increases(cleavage) CASP3 D014013 CTD decreases(reaction) CASP3 D014013 CTD increases(cleavage) CASP3 D014013 CTD decreases(reaction) CASP8 D014013 CTD increases(activity) CASP8 D014013 CTD affects(reaction) CASP9 D014013 CTD increases(cleavage) CASP9 D014013 CTD decreases(reaction) CASP9 D014013 CTD increases(cleavage) CASP9 D014013 CTD decreases(reaction) CCL2 D014013 CTD increases(expression) CCL2 D014013 CTD decreases(reaction) CDKN1A D014013 CTD increases(expression) CDKN1A D014013 CTD decreases(reaction) CTSB D014013 CTD increases(localization) CTSB D014013 CTD increases(expression) CXCL1 D014013 CTD decreases(reaction) FN1 D014013 CTD increases(expression) FN1 D014013 CTD decreases(reaction) HMOX1 D014013 CTD increases(activity) HMOX1 D014013 CTD increases(expression) HMOX1 D014013 CTD decreases(reaction) HMOX1 D014013 CTD increases(expression) HMOX1 D014013 CTD decreases(reaction) IL1B D014013 CTD increases(expression) IL1B D014013 CTD decreases(activity) IL24 D014013 CTD decreases(reaction) IL6 D014013 CTD increases(expression) IL6 D014013 CTD decreases(reaction) JAK2 D014013 CTD increases(phosphorylation) JAK2 D014013 CTD increases(reaction) JAK2 D014013 CTD decreases(reaction) MAPK1 D014013 CTD increases(abundance) MAPK1 D014013 CTD increases(activity) MAPK1 D014013 CTD increases(phosphorylation) MAPK1 D014013 CTD decreases(reaction) MAPK1 D014013 CTD increases(phosphorylation) MAPK1 D014013 CTD decreases(reaction) MAPK3 D014013 CTD increases(abundance) MAPK3 D014013 CTD increases(activity) MAPK3 D014013 CTD increases(phosphorylation) MAPK3 D014013 CTD decreases(reaction) MAPK3 D014013 CTD increases(phosphorylation) MAPK3 D014013 CTD decreases(reaction) MMP1 D014013 CTD increases(expression) MMP1 D014013 CTD decreases(reaction) MMP9 D014013 CTD increases(expression) MMP9 D014013 CTD increases(expression) NDRG1 D014013 CTD affects(localization) NFE2L2 D014013 CTD increases(activity) NFKB1 D014013 CTD affects(binding) NOS3 D014013 CTD decreases(expression) NOS3 D014013 CTD decreases(reaction) NOS3 D014013 CTD increases(activity) RELA D014013 CTD decreases(reaction) RHOA D014013 CTD increases(activity) RHOA D014013 CTD decreases(reaction) TGFB1 D014013 CTD increases(expression) TGFB1 D014013 CTD decreases(reaction) VCAM1 D014013 CTD increases(expression) VCAM1 D014013
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