Tan Lab | DSigDB

Gene Set: D4 : CTD - Thimerosal

Collection

D4 : CTD

Chemical Name

Thimerosal ( From PubChem : THIMEROSAL )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
404.811 g/mol	0	3	1.5779	True

Structure

InChI

InChI=1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2

InChIKey

RTKIYNMVFMVABJ-UHFFFAOYSA-L

Links

Gene (131 / 221)

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Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(secretion)			AIFM1		D013849
CTD	affects(binding)			ALB		D013849
CTD	increases(expression)			ARC		D013849
CTD	increases(expression)			ATF3		D013849
CTD	increases(expression)			BAG3		D013849
CTD	decreases(expression)			BIRC3		D013849
CTD	decreases(reaction)			BIRC3		D013849
CTD	decreases(reaction)			CASP3		D013849
CTD	increases(abundance)			CASP3		D013849
CTD	increases(activity)			CASP3		D013849
CTD	increases(cleavage)			CASP3		D013849
CTD	decreases(reaction)			CASP3		D013849
CTD	increases(activity)			CASP3		D013849
CTD	decreases(reaction)			CASP3		D013849
CTD	increases(activity)			CASP3		D013849
CTD	increases(activity)			CASP3		D013849
CTD	increases(cleavage)			CASP3		D013849
CTD	decreases(reaction)			CASP9		D013849
CTD	increases(activity)			CASP9		D013849
CTD	increases(cleavage)			CASP9		D013849
CTD	increases(activity)			CCNB1		D013849
CTD	increases(expression)			CCNB1		D013849
CTD	decreases(reaction)			CD86		D013849
CTD	increases(expression)			CD86		D013849
CTD	decreases(reaction)			CD86		D013849
CTD	increases(expression)			CD86		D013849
CTD	increases(expression)			CD86		D013849
CTD	decreases(expression)			CDK4		D013849
CTD	increases(expression)			CITED2		D013849
CTD	increases(expression)			CLU		D013849
CTD	increases(expression)			COL21A1		D013849
CTD	increases(expression)			CPEB3		D013849
CTD	increases(expression)			CRYAB		D013849
CTD	decreases(reaction)			CXCL8		D013849
CTD	increases(secretion)			CXCL8		D013849
CTD	increases(secretion)			CXCL8		D013849
CTD	increases(expression)			CYR61		D013849
CTD	increases(expression)			DNAJB1		D013849
CTD	increases(expression)			DNAJB4		D013849
CTD	increases(expression)			DUSP1		D013849
CTD	decreases(expression)			FANCF		D013849
CTD	increases(expression)			FOS		D013849
CTD	increases(expression)			FOSB		D013849
CTD	increases(expression)			GADD45G		D013849
CTD	decreases(expression)			GEMIN4		D013849
CTD	affects(response to substance)			GSTM1		D013849
CTD	affects(response to substance)			GSTT1		D013849
CTD	increases(expression)			HBEGF		D013849
CTD	increases(expression)			HIST1H3B		D013849
CTD	increases(expression)			HIST1H3G		D013849
CTD	increases(expression)			HMOX1		D013849
CTD	increases(expression)			HSPA1A		D013849
CTD	increases(expression)			HSPA1B		D013849
CTD	increases(expression)			HSPA1L		D013849
CTD	increases(expression)			HSPA6		D013849
CTD	increases(expression)			HSPB1		D013849
CTD	decreases(reaction)			IFNG		D013849
CTD	increases(secretion)			IFNG		D013849
CTD	affects(reaction)			IGF1		D013849
CTD	increases(activity)			IGF1		D013849
CTD	affects(cotreatment)			IL13		D013849
CTD	decreases(reaction)			IL13		D013849
CTD	increases(secretion)			IL13		D013849
CTD	affects(cotreatment)			IL5		D013849
CTD	increases(secretion)			IL5		D013849
CTD	decreases(reaction)			IL6		D013849
CTD	increases(secretion)			IL6		D013849
CTD	increases(expression)			JUN		D013849
CTD	increases(expression)			KANSL1L		D013849
CTD	increases(expression)			KLF4		D013849
CTD	increases(expression)			MAFB		D013849
CTD	decreases(phosphorylation)			MAPK1		D013849
CTD	decreases(reaction)			MAPK1		D013849
CTD	increases(phosphorylation)			MAPK14		D013849
CTD	decreases(phosphorylation)			MAPK3		D013849
CTD	decreases(reaction)			MAPK3		D013849
CTD	increases(phosphorylation)			MAPK3		D013849
CTD	increases(phosphorylation)			MAPK8		D013849
CTD	increases(phosphorylation)			MAPK9		D013849
CTD	decreases(expression)			MED18		D013849
CTD	affects(reaction)			MTR		D013849
CTD	increases(activity)			MTR		D013849
CTD	increases(expression)			MXD1		D013849
CTD	decreases(response to substance)			NGF		D013849
CTD	affects(cotreatment)			NGF		D013849
CTD	decreases(phosphorylation)			NGF		D013849
CTD	increases(expression)			NPAT		D013849
CTD	increases(expression)			NR4A1		D013849
CTD	increases(expression)			NR4A2		D013849
CTD	affects(cotreatment)			NTRK1		D013849
CTD	decreases(phosphorylation)			NTRK1		D013849
CTD	increases(expression)			PGF		D013849
CTD	decreases(expression)			PHF20L1		D013849
CTD	increases(cleavage)			PLCG1		D013849
CTD	increases(expression)			PLK2		D013849
CTD	decreases(reaction)			PTK2		D013849
CTD	increases(abundance)			PTK2		D013849
CTD	increases(activity)			PTK2		D013849
CTD	increases(cleavage)			PTK2		D013849
CTD	increases(response to substance)			PTK2		D013849
CTD	increases(expression)			RRAD		D013849
CTD	increases(expression)			SERPINE1		D013849
CTD	increases(expression)			SERPINH1		D013849
CTD	increases(expression)			TMOD2		D013849
CTD	decreases(reaction)			TNF		D013849
CTD	increases(secretion)			TNF		D013849
CTD	increases(secretion)			TNF		D013849
CTD	decreases(activity)			TOP2A		D013849
CTD	increases(expression)			UPP1		D013849
CTD	decreases(expression)			XIAP		D013849
CTD	decreases(reaction)			XIAP		D013849
CTD	affects(expression)			XIAP		D013849
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	None	uM		ABHD5	-	GI(Protien) :
PubChem	Potency	uM	0.178	ALDH1A1	-	GI(Protien) :
PubChem	Potency	uM	1.259	ALOX15	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.548	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.090	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	7.696	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.439	AR	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	9.521	AR	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.974	AR	-	GI(Protien) :
PubChem	Potency	uM	4.467	ATXN2	-	GI(Protien) :
PubChem	AC50_uM	uM	6.910	CASP6	-	GI(Protien) :
PubChem	None	uM		CASP6	-	GI(Protien) :
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CHRM4	-	GI(Protien) :
PubChem	None	uM		CTDSP1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	1.087	CYP19A1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	5.956	CYP19A1	-	GI(Protien) :
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	4.500	ESR1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	21.878	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	30.107	ESR1	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	54.941	ESR1	-	GI(Protien) :
PubChem	Potency	uM	22.387	FEN1	-	GI(Protien) :
PubChem	Potency	uM	0.750	GMNN	-	GI(Protien) :
PubChem	Potency	uM	0.920	GMNN	-	GI(Protien) :
PubChem	Potency	uM	5.957	GMNN	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		GNA15	-	GI(Protien) :
PubChem	None	uM		GNAI1	-	GI(Protien) :
PubChem	None	uM		HCRTR1	-	GI(Protien) :
PubChem	None	uM		HDAC3	-	GI(Protien) :
PubChem	None	uM		HNF4A	-	GI(Protien) :
PubChem	Potency	uM	0.282	HPGD	-	GI(Protien) :
PubChem	AC50_uM	uM	2.311	HSP90AA1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	1.548	HSPB1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	9.438	HSPB1	-	GI(Protien) :
PubChem	Potency	uM	2.512	HTT	-	GI(Protien) :
PubChem	None	uM		IDE	-	GI(Protien) :
PubChem	None	uM		IDE	-	GI(Protien) :
PubChem	Potency	uM	2.311	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	Potency	uM	10.000	MAPK1	-	GI(Protien) :
PubChem	Potency	uM	31.623	MAPK1	-	GI(Protien) :
PubChem	None	uM		MC4R	-	GI(Protien) :
PubChem	None	uM		MC4R	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM2	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MDM4	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		MRGPRX1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.331	NFE2L2	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.619	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	None	uM		NLRP3	-	GI(Protien) :
PubChem	IC50	uM	1.402	NOD2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	Potency	uM	8.912	NR1H4	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	14.959	NR1H4	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	EC50_Mean	uM	4.370	NTSR1	-	GI(Protien) :
PubChem	None	uM		NTSR1	-	GI(Protien) :
PubChem	None	uM		NTSR1	-	GI(Protien) :
PubChem	None	uM		OXTR	-	GI(Protien) :
PubChem	None	uM		PADI4	-	GI(Protien) :
PubChem	None	uM		PADI4	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	None	uM		PLIN5	-	GI(Protien) :
PubChem	Potency	uM	2.668	PLK1	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	3.890	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	7.497	PPARD	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	0.462	PPARG	-	GI(Protien) :
PubChem	Ratio Potency (uM)	uM	2.215	PPARG	-	GI(Protien) :
PubChem	None	uM		PRMT1	-	GI(Protien) :
PubChem	None	uM		PTGER2	-	GI(Protien) :
PubChem	None	uM		RGS12	-	GI(Protien) :
PubChem	IC50	uM	1.402	RIPK2	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	Potency	uM	2.239	RXRA	-	GI(Protien) :
PubChem	Potency	uM	4.467	SMAD3	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	None	uM		TAAR1	-	GI(Protien) :
PubChem	Potency	uM	0.206	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.411	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.581	TDP1	-	GI(Protien) :
PubChem	IC50	uM	6.339	TLR9	-	GI(Protien) :
PubChem	None	uM		TLR9	-	GI(Protien) :
PubChem	None	uM		TLR9	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	None	uM		TNNC1	-	GI(Protien) :
PubChem	None	uM		TNNI3	-	GI(Protien) :
PubChem	None	uM		TNNT2	-	GI(Protien) :
PubChem	Potency	uM	1.000	TP53	-	GI(Protien) :
PubChem	Potency	uM	1.259	TP53	-	GI(Protien) :
PubChem	Potency-Replicate_1	uM	3.378	VDR	-	GI(Protien) :
PubChem	Potency	uM	11.220	VDR	-	GI(Protien) :
PubChem	Potency	uM	79.433	VDR	-	GI(Protien) :

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