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Drug SIGnatures DataBase

Collection of Annoated Drug / Compound Gene Sets

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Gene Set: D4 : CTD - Taurine

Collection

D4 : CTD

Chemical Name

Taurine ( From PubChem : TAURINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Approved	Not	Not	Approved	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
125.147 g/mol	2	4	0.614	True

Structure

InChI

InChI=1S/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H,4,5,6)

InChIKey

XOAAWQZATWQOTB-UHFFFAOYSA-N

Links

Gene (57 / 60)

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Source	Type	Unit	Value	Gene	PMID	Assay	Other
CTD	increases(expression)			ABL2			D013654
CTD	increases(expression)			ADAP2			D013654
CTD	decreases(expression)			ADORA2A			D013654
CTD	increases(expression)			ADRA1B			D013654
CTD	decreases(expression)			BID			D013654
CTD	decreases(expression)			BMPR2			D013654
CTD	decreases(expression)			CAP2			D013654
CTD	increases(expression)			CAP2			D013654
CTD	increases(expression)			CGA			D013654
CTD	decreases(expression)			CHN1			D013654
CTD	increases(expression)			COPS2			D013654
CTD	decreases(expression)			CXCR3			D013654
CTD	decreases(expression)			DDAH1			D013654
CTD	increases(expression)			DGKZ			D013654
CTD	increases(expression)			EI24			D013654
CTD	increases(secretion)			FAS			D013654
CTD	decreases(expression)			FGFR1			D013654
CTD	affects(binding)			GLRA1			D013654
CTD	increases(activity)			GLRA1			D013654
CTD	decreases(expression)			GRM7			D013654
CTD	decreases(expression)			GUCY1A3			D013654
CTD	decreases(expression)			HMGB1			D013654
CTD	decreases(expression)			IGFBP3			D013654
CTD	increases(expression)			KRIT1			D013654
CTD	increases(expression)			LANCL1			D013654
CTD	decreases(expression)			LYN			D013654
CTD	decreases(expression)			MS4A6A			D013654
CTD	decreases(expression)			OR51E2			D013654
CTD	decreases(expression)			PAG1			D013654
CTD	decreases(expression)			PAK4			D013654
CTD	increases(expression)			POLB			D013654
CTD	increases(expression)			POLD1			D013654
CTD	increases(expression)			POLM			D013654
CTD	increases(expression)			PPP1R16B			D013654
CTD	decreases(expression)			PPP2R5E			D013654
CTD	decreases(expression)			PRKAR2B			D013654
CTD	decreases(expression)			PSEN2			D013654
CTD	decreases(expression)			PTPRK			D013654
CTD	decreases(expression)			RAB5A			D013654
CTD	increases(expression)			RAD51C			D013654
CTD	increases(expression)			RAD9A			D013654
CTD	decreases(expression)			RAPGEF2			D013654
CTD	increases(expression)			RASGRP1			D013654
CTD	increases(expression)			RPS6KA2			D013654
CTD	increases(expression)			SCG5			D013654
CTD	increases(expression)			SMC3			D013654
CTD	increases(expression)			SNAPC5			D013654
CTD	increases(expression)			SPRY2			D013654
CTD	decreases(expression)			SRP54			D013654
CTD	decreases(expression)			STAT3			D013654
CTD	decreases(expression)			TACR1			D013654
CTD	increases(expression)			TEK			D013654
CTD	decreases(reaction)			TGFB1			D013654
CTD	increases(expression)			TGFB1			D013654
CTD	decreases(expression)			TP53I3			D013654
CTD	decreases(expression)			TYK2			D013654
CTD	decreases(expression)			VCP			D013654
CTD	increases(expression)			XRCC4			D013654
PubChem	AhR Potency (uM)	uM	28.372	AHR	-		GI(Protien) :
PubChem	Ratio Potency (uM)	uM	13.684	NFE2L2	-		GI(Protien) :

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Tan Lab , Mail Stop 8117
12801 East 17th Avenue
Division of Medical Oncology , Department of Medicine
University of Colorado School of Medicine
Aurora, CO 80045, USA

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