Tan Lab | DSigDB

Gene Set: D4 : CTD - T-2 Toxin

Collection

D4 : CTD

Chemical Name

T-2 Toxin ( From PubChem : T-2 TOXIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
466.521 g/mol	1	9	1.6927	True

Structure

InChI

InChI=1S/C24H34O9/c1-12(2)7-18(27)32-16-9-23(10-29-14(4)25)17(8-13(16)3)33-21-19(28)20(31-15(5)26)22(23,6)24(21)11-30-24/h8,12,16-17,19-21,28H,7,9-11H2,1-6H3/t16-,17+,19+,20+,21+,22+,23+,24+/m0/s1

InChIKey

BXFOFFBJRFZBQZ-FHAHJZMBSA-N

Links

Gene (47 / 85)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	decreases(expression)			A2M		D013605
CTD	decreases(reaction)			A2M		D013605
CTD	increases(reaction)			A2M		D013605
CTD	decreases(expression)			ACAN		D013605
CTD	decreases(expression)			ACAN		D013605
CTD	increases(expression)			ADAMTS5		D013605
CTD	increases(phosphorylation)			ATM		D013605
CTD	decreases(reaction)			BAX		D013605
CTD	increases(expression)			BAX		D013605
CTD	affects(localization)			BAX		D013605
CTD	increases(expression)			BAX		D013605
CTD	increases(expression)			BCL2		D013605
CTD	increases(activity)			CASP3		D013605
CTD	increases(activity)			CASP7		D013605
CTD	increases(activity)			CASP9		D013605
CTD	decreases(expression)			CD44		D013605
CTD	decreases(reaction)			CD44		D013605
CTD	decreases(reaction)			CHEK2		D013605
CTD	increases(activity)			CHEK2		D013605
CTD	decreases(reaction)			CXCL8		D013605
CTD	increases(reaction)			CXCL8		D013605
CTD	increases(secretion)			CXCL8		D013605
CTD	increases(expression)			CXCL8		D013605
CTD	affects(localization)			CYCS		D013605
CTD	decreases(expression)			CYP19A1		D013605
CTD	decreases(reaction)			CYP1A1		D013605
CTD	increases(expression)			CYP1A1		D013605
CTD	increases(reaction)			CYP1A1		D013605
CTD	increases(expression)			CYP1A1		D013605
CTD	increases(expression)			CYP21A2		D013605
CTD	decreases(reaction)			H2AFX		D013605
CTD	increases(activity)			H2AFX		D013605
CTD	decreases(expression)			HAS2		D013605
CTD	decreases(expression)			HMGCR		D013605
CTD	decreases(reaction)			IL1B		D013605
CTD	increases(reaction)			IL1B		D013605
CTD	increases(secretion)			IL1B		D013605
CTD	increases(expression)			IL1B		D013605
CTD	increases(reaction)			IL1B		D013605
CTD	increases(expression)			IL1B		D013605
CTD	increases(expression)			MMP1		D013605
CTD	decreases(reaction)			MMP13		D013605
CTD	increases(expression)			MMP13		D013605
CTD	decreases(expression)			NR0B1		D013605
CTD	decreases(expression)			NR5A1		D013605
CTD	decreases(expression)			TIMP1		D013605
CTD	decreases(reaction)			TIMP1		D013605
CTD	decreases(expression)			TIMP2		D013605
CTD	decreases(reaction)			TIMP2		D013605
CTD	increases(expression)			TNF		D013605
CTD	increases(reaction)			TNF		D013605
CTD	increases(expression)			TP53		D013605
PubChem	None	uM		CFTR	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		EPAS1	-	GI(Protien) :
PubChem	None	uM		HIF1A	-	GI(Protien) :
PubChem	Potency	uM	0.259	IDH1	-	GI(Protien) :
PubChem	None	uM		IL1B	-	GI(Protien) :
PubChem	None	uM		MITF	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA1	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA2	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	None	uM		NCOA3	-	GI(Protien) :
PubChem	Potency	uM	0.021	NFE2L2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NOD2	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2E3	-	GI(Protien) :
PubChem	None	uM		NR2F2	-	GI(Protien) :
PubChem	None	uM		NR5A1	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		NR5A2	-	GI(Protien) :
PubChem	None	uM		PAX8	-	GI(Protien) :
PubChem	None	uM		PRNP	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	None	uM		RIPK2	-	GI(Protien) :
PubChem	Potency	uM	0.005	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.010	SMAD3	-	GI(Protien) :
PubChem	Potency	uM	0.023	TDP1	-	GI(Protien) :
PubChem	Potency	uM	0.023	TDP1	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :
PubChem	None	uM		TNFRSF10B	-	GI(Protien) :

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