Tan Lab | DSigDB

Gene Set: D4 : CTD - Sulpiride

Collection

D4 : CTD

Chemical Name

Sulpiride ( From PubChem : SULPIRIDE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Approved	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
341.426 g/mol	2	7	2.6666	True

Structure

InChI

InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1

InChIKey

Links

Gene (14 / 32)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			CA2		D013469
CTD	decreases(activity)			CA2		D013469
CTD	affects(binding)			CA3		D013469
CTD	decreases(activity)			CA3		D013469
CTD	affects(binding)			DRD2		D013469
CTD	affects(binding)			DRD2		D013469
CTD	decreases(reaction)			DRD2		D013469
CTD	decreases(transport)			DRD2		D013469
CTD	increases(activity)			DRD2		D013469
CTD	increases(expression)			INS		D013469
CTD	affects(binding)			KCNH1		D013469
CTD	decreases(activity)			KCNH1		D013469
CTD	increases(abundance)			PRL		D013469
CTD	increases(expression)			PRL		D013469
CTD	increases(secretion)			PRL		D013469
CTD	decreases(reaction)			PRL		D013469
CTD	decreases(reaction)			PRL		D013469
CTD	increases(secretion)			PRL		D013469
CTD	affects(localization)			SLC6A3		D013469
CTD	decreases(reaction)			SLC6A3		D013469
CTD	increases(uptake)			SLC6A3		D013469
PubChem	None	uM		DRD3	-	GI(Protien) :
PubChem	Potency	uM	10.000	KCNH2		GI(Protien) :
PubChem	Potency	uM	10.000	KCNH2		GI(Protien) :
ChEMBL	Inhibition	-		CYP1A2	-	Target : CHEMBL3356
ChEMBL	Inhibition	-		CYP2C19	-	Target : CHEMBL3622
ChEMBL	Inhibition	-		CYP2C9	-	Target : CHEMBL3397
ChEMBL	Inhibition	-		CYP2D6	-	Target : CHEMBL289
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Inhibition	-		CYP3A4	-	Target : CHEMBL340
ChEMBL	Activity	-		DRD2	-	Target : CHEMBL217
ChEMBL	Activity	-		DRD3	-	Target : CHEMBL234

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