Tan Lab | DSigDB

Gene Set: D4 : CTD - Spermine

Collection

D4 : CTD

Chemical Name

Spermine ( From PubChem : SPERMINE )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
202.34 g/mol	4	4	1.8258	True

Structure

InChI

InChI=1S/C10H26N4/c11-5-3-9-13-7-1-2-8-14-10-4-6-12/h13-14H,1-12H2

InChIKey

Links

Gene (14 / 24)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	affects(binding)			ADRB1		D013096
CTD	affects(binding)			ADRB2		D013096
CTD	decreases(expression)			BCL2		D013096
CTD	affects(binding)			CASR		D013096
CTD	decreases(reaction)			CASR		D013096
CTD	increases(activity)			CASR		D013096
CTD	increases(uptake)			CASR		D013096
CTD	affects(localization)			DIABLO		D013096
CTD	decreases(reaction)			MAPK8		D013096
CTD	increases(activity)			MAPK8		D013096
CTD	decreases(reaction)			NOS2		D013096
CTD	increases(activity)			NOS2		D013096
CTD	increases(oxidation)			SMOX		D013096
CTD	increases(abundance)			SMOX		D013096
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	7.943	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	4.611	DRD1	-	GI(Protien) :
PubChem	Potency	uM	12.589	EHMT2	-	GI(Protien) :
ChEMBL	Activity	-		CASP2	-	Target : CHEMBL4884
ChEMBL	Activity	-		CASP3	-	Target : CHEMBL2334
ChEMBL	Potency	nM	7943.300	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	7943.280	CYP2C19	-	Target : CHEMBL3622
ChEMBL	Potency	nM	12589.300	EHMT2	-	Target : CHEMBL6032

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