Tan Lab | DSigDB

Gene Set: D4 : CTD - dihydrocapsaicin

Collection

D4 : CTD

Chemical Name

dihydrocapsaicin ( From PubChem : DIHYDROCAPSAICIN )

FDA	NPC	WHO	Indian	Australia	China	Traditional Herbal	Clinical Trail
Not	Not	Not	Not	Not	Not	Not	Not

Molecular Weight	Hydrogen Bond Donor Count	Hydrogen Bond Acceptor Count	cLogP	Lipinski Rule
307.428 g/mol	2	4	4.4045	True

Structure

InChI

InChI=1S/C18H29NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h10-12,14,20H,4-9,13H2,1-3H3,(H,19,21)

InChIKey

XJQPQKLURWNAAH-UHFFFAOYSA-N

Links

Gene (21 / 57)

⊖ Less

Source	Type	Unit	Value	Gene	PMID	Other
CTD	increases(expression)			ATF4		C012906
CTD	increases(activity)			CASP3		C012906
CTD	increases(reaction)			CASP3		C012906
CTD	decreases(reaction)			CASP3		C012906
CTD	increases(activity)			CASP3		C012906
CTD	increases(activity)			CASP4		C012906
CTD	increases(cleavage)			CASP4		C012906
CTD	increases(activity)			CASP7		C012906
CTD	affects(reaction)			CAT		C012906
CTD	decreases(abundance)			CAT		C012906
CTD	increases(expression)			CAT		C012906
CTD	decreases(expression)			CAT		C012906
CTD	increases(abundance)			CAT		C012906
CTD	decreases(abundance)			CAT		C012906
CTD	increases(expression)			CAT		C012906
CTD	increases(expression)			CDKN1A		C012906
CTD	decreases(activity)			CYP1A2		C012906
CTD	decreases(activity)			CYP2C19		C012906
CTD	decreases(activity)			CYP2C9		C012906
CTD	decreases(activity)			CYP2D6		C012906
CTD	decreases(reaction)			DDIT3		C012906
CTD	increases(expression)			DDIT3		C012906
CTD	increases(activity)			DDIT3		C012906
CTD	increases(phosphorylation)			EIF2S1		C012906
CTD	decreases(reaction)			ERN1		C012906
CTD	increases(expression)			ERN1		C012906
CTD	increases(expression)			HSPA5		C012906
CTD	decreases(reaction)			MAP1LC3A		C012906
CTD	increases(expression)			MAP1LC3A		C012906
CTD	increases(reaction)			MAP1LC3A		C012906
CTD	affects(reaction)			MAP1LC3A		C012906
CTD	increases(activity)			MAPK1		C012906
CTD	increases(phosphorylation)			MAPK1		C012906
CTD	increases(activity)			MAPK3		C012906
CTD	increases(phosphorylation)			MAPK3		C012906
CTD	increases(phosphorylation)			TP53		C012906
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	None	uM		CYP1A2	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2C19	-	GI(Protien) :
PubChem	None	uM		CYP2C19	-	GI(Protien) :
PubChem	Potency	uM	2.512	CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	10.000	CYP2C9	-	GI(Protien) :
PubChem	None	uM		CYP2C9	-	GI(Protien) :
PubChem	Potency	uM	12.589	CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	25.119	CYP3A4	-	GI(Protien) :
PubChem	None	uM		CYP3A4	-	GI(Protien) :
PubChem	Potency	uM	3.162	GLS	-	GI(Protien) :
PubChem	None	uM		PLA2G7	-	GI(Protien) :
ChEMBL	AC50	nM	12589.200	CYP1A2	-	Target : CHEMBL3356
ChEMBL	Potency	nM	10000.000	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	10000.000	CYP2C19	-	Target : CHEMBL3622
ChEMBL	AC50	nM	2511.890	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	10000.000	CYP2C9	-	Target : CHEMBL3397
ChEMBL	Potency	nM	2511.900	CYP2C9	-	Target : CHEMBL3397
ChEMBL	AC50	nM	12589.200	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	12589.300	CYP3A4	-	Target : CHEMBL340
ChEMBL	Potency	nM	25118.900	CYP3A4	-	Target : CHEMBL340

Download gene sets

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